Artículo
Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
Peichoto, María Elisa
; Paes Leme, Adriana F.; Pauletti, Bianca A.; Correia Batista, Isabel; Mackessy, Stephen P.; Acosta, Ofelia Cristina
; Santoro, Marcelo Larami


Fecha de publicación:
09/2010
Editorial:
Elsevier Science
Revista:
Biochimica Et Biophysica Acta-proteins And Proteomics
ISSN:
1570-9639
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Patago-calcium markedly enhanced the azocaseinolytic activity of patagonfibrase. Our findings contribute to the understanding of the structural and mechanistic bases of this family of metalloenzymes that are widely distributed among snake venoms, demonstrating that important post-translational modifications such as proteolysis can also contribute to the diversity and complexity of proteins found in rear-fanged snake venoms.
Palabras clave:
Autodegradation
,
Colubridae
,
Metalloproteinase
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Identificadores
Colecciones
Articulos(CCT - NORDESTE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NORDESTE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NORDESTE
Citación
Peichoto, María Elisa; Paes Leme, Adriana F.; Pauletti, Bianca A.; Correia Batista, Isabel; Mackessy, Stephen P.; et al.; Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom; Elsevier Science; Biochimica Et Biophysica Acta-proteins And Proteomics; 1804; 9; 9-2010; 1937-1942
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