Repositorio Institucional
Repositorio Institucional
CONICET Digital
  • Inicio
  • EXPLORAR
    • AUTORES
    • DISCIPLINAS
    • COMUNIDADES
  • Estadísticas
  • Novedades
    • Noticias
    • Boletines
  • Ayuda
    • General
    • Datos de investigación
  • Acerca de
    • CONICET Digital
    • Equipo
    • Red Federal
  • Contacto
JavaScript is disabled for your browser. Some features of this site may not work without it.
  • INFORMACIÓN GENERAL
  • RESUMEN
  • ESTADISTICAS
 
Artículo

Self-sufficient redox biotransformation of lignin-related benzoic acids with Aspergillus flavus

Palazzolo, Martín AlejandroIcon ; Mascotti, María LauraIcon ; Lewkowicz, Elizabeth SandraIcon ; Kurina Sanz, Marcela BeatrizIcon
Fecha de publicación: 10/2015
Editorial: Springer
Revista: Journal of Industrial Microbiology & Biotechnology
ISSN: 1367-5435
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:
Bioprocesamiento Tecnológico, Biocatálisis, Fermentación

Resumen

Aromatic carboxylic acids are readily obtained from lignin in biomass processing facilities. However, efficient technologies for lignin valorization are missing. In this work, a microbial screening was conducted to find versatile biocatalysts capable of transforming several benzoic acids structurally related to lignin, employing vanillic acid as model substrate. The wild-type Aspergillus flavus growing cells exhibited exquisite selectivity towards the oxidative decarboxylation product, 2-methoxybenzene-1,4-diol. Interestingly, when assaying a set of structurally-related substrates, the biocatalyst displayed the oxidative removal of the carboxyl moiety or its reduction to the primary alcohol whether electron withdrawing or donating groups were present in the aromatic ring, respectively. Additionally, A. flavus proved to be highly tolerant to vanillic acid increasing concentrations (up to 8 g/L), demonstrating its potential application in chemical synthesis. A. flavus growing cells were found to be efficient biotechnological tools to perform self-sufficient, structure-dependent redox reactions. All the biotransformations described herein are reported for the first time.
Palabras clave: Benzoic , Redox Biotransformation , Aspergillus Flavus , Acids Carboxyl Reduction , Oxidative Decarboxylation
Ver el registro completo
 
Archivos asociados
Thumbnail
 
Tamaño: 1.013Mb
Formato: PDF
.
Descargar
Licencia
info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/5843
URL: http://link.springer.com/article/10.1007%2Fs10295-015-1696-4
DOI: http://dx.doi.org/10.1007/s10295-015-1696-4
DOI: http://dx.doi.org/ 10.1007/s10295-015-1696-4
Colecciones
Articulos(IMIBIO-SL)
Articulos de INST. MULTIDICIPLINARIO DE INV. BIO. DE SAN LUIS
Articulos(INTEQUI)
Articulos de INST. DE INVEST. EN TECNOLOGIA QUIMICA
Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Citación
Palazzolo, Martín Alejandro; Mascotti, María Laura; Lewkowicz, Elizabeth Sandra; Kurina Sanz, Marcela Beatriz; Self-sufficient redox biotransformation of lignin-related benzoic acids with Aspergillus flavus; Springer; Journal of Industrial Microbiology & Biotechnology; 42; 12; 10-2015; 1581-1589
Compartir
Altmétricas
 

Enviar por e-mail
Separar cada destinatario (hasta 5) con punto y coma.
  • Facebook
  • X Conicet Digital
  • Instagram
  • YouTube
  • Sound Cloud
  • LinkedIn

Los contenidos del CONICET están licenciados bajo Creative Commons Reconocimiento 2.5 Argentina License

https://www.conicet.gov.ar/ - CONICET

Inicio

Explorar

  • Autores
  • Disciplinas
  • Comunidades

Estadísticas

Novedades

  • Noticias
  • Boletines

Ayuda

Acerca de

  • CONICET Digital
  • Equipo
  • Red Federal

Contacto

Godoy Cruz 2290 (C1425FQB) CABA – República Argentina – Tel: +5411 4899-5400 repositorio@conicet.gov.ar
TÉRMINOS Y CONDICIONES