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dc.contributor.author
Cardama, Georgina Alexandra  
dc.contributor.author
Lorenzano Menna, Pablo  
dc.date.available
2018-08-28T21:18:54Z  
dc.date.issued
2015-07  
dc.identifier.citation
Cardama, Georgina Alexandra; Lorenzano Menna, Pablo; Dynamic interaction between glioma cells and their microenvironment: targeting Rac1 as a therapeutic approach; Smart Science and Technology; Cancer Cell & Microenvironment; 2; 3; 7-2015; 1-4  
dc.identifier.issn
2331-0928  
dc.identifier.uri
http://hdl.handle.net/11336/57448  
dc.description.abstract
Rac1 has been described as a major player in glioma invasion and progression. The development of novel anti Rac1 inhibitors, such as 1A-116, provides a targeted rational approach to counteract glioma progression. This therapeutic strategy could affect the glioma cell behavior as well as its interplay with the microenvironment. Further studies are needed to validate the effectiveness of this novel molecules and their use in glioma progression.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Smart Science and Technology  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Glioma  
dc.subject
Rho-Gtpases  
dc.subject
Targeted Terapies  
dc.subject
Rational Design  
dc.subject.classification
Otras Biotecnologías de la Salud  
dc.subject.classification
Biotecnología de la Salud  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Dynamic interaction between glioma cells and their microenvironment: targeting Rac1 as a therapeutic approach  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-08-16T18:05:23Z  
dc.journal.volume
2  
dc.journal.number
3  
dc.journal.pagination
1-4  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Houston  
dc.description.fil
Fil: Cardama, Georgina Alexandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Oncología Molecular; Argentina  
dc.description.fil
Fil: Lorenzano Menna, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Oncología Molecular; Argentina  
dc.journal.title
Cancer Cell & Microenvironment  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.smartscitech.com/index.php/CCM/article/view/866