Artículo

Dynamic interaction between glioma cells and their microenvironment: targeting Rac1 as a therapeutic approach

Cardama, Georgina AlexandraIcon ; Lorenzano Menna, PabloIcon
Fecha de publicación: 07/2015
Editorial: Smart Science and Technology
Revista: Cancer Cell & Microenvironment
ISSN: 2331-0928
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Rac1 has been described as a major player in glioma invasion and progression. The development of novel anti Rac1 inhibitors, such as 1A-116, provides a targeted rational approach to counteract glioma progression. This therapeutic strategy could affect the glioma cell behavior as well as its interplay with the microenvironment. Further studies are needed to validate the effectiveness of this novel molecules and their use in glioma progression.
Palabras clave: Glioma , Rho-Gtpases , Targeted Terapies , Rational Design
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/57448
URL: http://www.smartscitech.com/index.php/CCM/article/view/866
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Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Citación
Cardama, Georgina Alexandra; Lorenzano Menna, Pablo; Dynamic interaction between glioma cells and their microenvironment: targeting Rac1 as a therapeutic approach; Smart Science and Technology; Cancer Cell & Microenvironment; 2; 3; 7-2015; 1-4
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