Mostrar el registro sencillo del ítem
dc.contributor.author
Maggini, Julian
dc.contributor.author
Raiden, Silvina Claudia
dc.contributor.author
Salamone, Gabriela Veronica
dc.contributor.author
Trevani, Analía Silvina
dc.contributor.author
Geffner, Jorge Raúl
dc.date.available
2018-08-14T15:18:36Z
dc.date.issued
2009-01
dc.identifier.citation
Maggini, Julian; Raiden, Silvina Claudia; Salamone, Gabriela Veronica; Trevani, Analía Silvina; Geffner, Jorge Raúl; Regulation of neutrophil apoptosis by cytokines, pathogens and environmental stressors; Frontiers in Bioscience; Frontiers in Bioscience; 14; 6; 1-2009; 2372-2385
dc.identifier.issn
1093-9946
dc.identifier.uri
http://hdl.handle.net/11336/55359
dc.description.abstract
As a key component of the innate immune response, neutrophils play a major role in host protection against bacterial and fungi infections. Neutrophils are short-lived phagocytic cells and, as a first line of defense against host insult, they are rapidly and massively recruited from the circulation into inflammatory sites, where the expression of their apoptotic program can be regulated by a number of agents such as cytokines, pathogens and environmental stressors. Apoptosis of neutrophils is central to homoeostasis and the resolution of inflammation. Recent studies have highlighted the complex convergence of different pathways in the regulation of neutrophil survival. This review focuses on the mechanisms involved in the induction and regulation of neutrophil apoptosis.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Frontiers in Bioscience
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Apoptosis
dc.subject
Extrinsic Pathway
dc.subject
Fas
dc.subject
Intrinsic Pathway
dc.subject
Mitochondria
dc.subject
Neutrophils
dc.subject
Review
dc.subject.classification
Inmunología
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Regulation of neutrophil apoptosis by cytokines, pathogens and environmental stressors
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-08-14T13:58:49Z
dc.journal.volume
14
dc.journal.number
6
dc.journal.pagination
2372-2385
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Nueva York
dc.description.fil
Fil: Maggini, Julian. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina
dc.description.fil
Fil: Raiden, Silvina Claudia. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Salamone, Gabriela Veronica. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Trevani, Analía Silvina. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Geffner, Jorge Raúl. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Frontiers in Bioscience
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2741/3384
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.bioscience.org/2009/v14/af/3384/list.htm
Archivos asociados