Artículo
Regulation of neutrophil apoptosis by cytokines, pathogens and environmental stressors
Maggini, Julian; Raiden, Silvina Claudia
; Salamone, Gabriela Veronica
; Trevani, Analía Silvina
; Geffner, Jorge Raúl




Fecha de publicación:
01/2009
Editorial:
Frontiers in Bioscience
Revista:
Frontiers in Bioscience
ISSN:
1093-9946
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
As a key component of the innate immune response, neutrophils play a major role in host protection against bacterial and fungi infections. Neutrophils are short-lived phagocytic cells and, as a first line of defense against host insult, they are rapidly and massively recruited from the circulation into inflammatory sites, where the expression of their apoptotic program can be regulated by a number of agents such as cytokines, pathogens and environmental stressors. Apoptosis of neutrophils is central to homoeostasis and the resolution of inflammation. Recent studies have highlighted the complex convergence of different pathways in the regulation of neutrophil survival. This review focuses on the mechanisms involved in the induction and regulation of neutrophil apoptosis.
Palabras clave:
Apoptosis
,
Extrinsic Pathway
,
Fas
,
Intrinsic Pathway
,
Mitochondria
,
Neutrophils
,
Review
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Articulos(IMEX)
Articulos de INST.DE MEDICINA EXPERIMENTAL
Articulos de INST.DE MEDICINA EXPERIMENTAL
Articulos(INIGEM)
Articulos de INSTITUTO DE INMUNOLOGIA, GENETICA Y METABOLISMO
Articulos de INSTITUTO DE INMUNOLOGIA, GENETICA Y METABOLISMO
Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Maggini, Julian; Raiden, Silvina Claudia; Salamone, Gabriela Veronica; Trevani, Analía Silvina; Geffner, Jorge Raúl; Regulation of neutrophil apoptosis by cytokines, pathogens and environmental stressors; Frontiers in Bioscience; Frontiers in Bioscience; 14; 6; 1-2009; 2372-2385
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