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dc.contributor.author
Fundia, Ariela Freya  
dc.contributor.author
Acevedo, Susana Haydee  
dc.contributor.author
Larripa, Irene Beatriz  
dc.date.available
2018-08-13T14:36:11Z  
dc.date.issued
2000-10  
dc.identifier.citation
Fundia, Ariela Freya; Acevedo, Susana Haydee; Larripa, Irene Beatriz; Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites; Ferrata Storti Foundation; Haematologica; 85; 10; 10-2000; 1104-1106  
dc.identifier.issn
0390-6078  
dc.identifier.uri
http://hdl.handle.net/11336/55098  
dc.description.abstract
Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. 85(10):October 2000 leukemia, suggesting the presence of chromosome instability. Bands 9q34 or 22q11 were not damaged in these patients, demonstrating that the origin of the Philadelphia chromosome is independent of spontaneous breakage or fragile site expression.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Ferrata Storti Foundation  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Chronic Myeloid Leukemia  
dc.subject
Chromosome Fragile Sites  
dc.subject
Spontaneous Chromosome Aberrations  
dc.subject
Philadelphia Rearrangement  
dc.subject.classification
Inmunología  
dc.subject.classification
Medicina Básica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-08-08T14:48:15Z  
dc.identifier.eissn
1592-8721  
dc.journal.volume
85  
dc.journal.number
10  
dc.journal.pagination
1104-1106  
dc.journal.pais
Italia  
dc.journal.ciudad
Pavia  
dc.description.fil
Fil: Fundia, Ariela Freya. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina  
dc.description.fil
Fil: Acevedo, Susana Haydee. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas ; Argentina  
dc.description.fil
Fil: Larripa, Irene Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina  
dc.journal.title
Haematologica  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.haematologica.org/content/85/10/1104.long  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/pmid/11025611