Artículo

Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites

Fundia, Ariela FreyaIcon ; Acevedo, Susana Haydee; Larripa, Irene BeatrizIcon
Fecha de publicación: 10/2000
Editorial: Ferrata Storti Foundation
Revista: Haematologica
ISSN: 0390-6078
e-ISSN: 1592-8721
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. 85(10):October 2000 leukemia, suggesting the presence of chromosome instability. Bands 9q34 or 22q11 were not damaged in these patients, demonstrating that the origin of the Philadelphia chromosome is independent of spontaneous breakage or fragile site expression.
Palabras clave: Chronic Myeloid Leukemia , Chromosome Fragile Sites , Spontaneous Chromosome Aberrations , Philadelphia Rearrangement
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
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URI: http://hdl.handle.net/11336/55098
URL: http://www.haematologica.org/content/85/10/1104.long
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Citación
Fundia, Ariela Freya; Acevedo, Susana Haydee; Larripa, Irene Beatriz; Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites; Ferrata Storti Foundation; Haematologica; 85; 10; 10-2000; 1104-1106
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