Artículo
Antioxidant and anti-inflammatory activity characterization and genotoxicity evaluation of Ziziphus mistol ripe berries, exotic Argentinean fruit
Cardozo, María Luz
; Ordóñez, Roxana Mabel
; Alberto, Maria Rosa
; Zampini, Iris Catiana
; Isla, Maria Ines
Fecha de publicación:
08/2011
Editorial:
Elsevier Science
Revista:
Food Research International
ISSN:
0963-9969
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Ziziphus mistol Griseb. (Rhamnaceae), popularly known as 'mistol' is widely distributed throughout Perú, Bolivia, Paraguay and Argentina. Its fruit is consumed in different forms in several Argentinean communities. The aim of this work is to quantify Z. mistol fruit macronutrients and phytochemicals as well as to determine its functional antioxidant and anti-inflammatory properties and toxicity after two different processes: boiling and hydroalcoholic extraction. Phytochemical recovery was variable depending on the extraction method used. All preparations showed antioxidant activity, but the ethanolic one (EME) was significantly more active than the aqueous one (AME) as hydrogen or electron donors with SC50 values between 1.45 to 6.31 μg GAE/mL and 7.38 to 64.77 μg GAE/mL, respectively. The aqueous extraction was significantly more active than EME on superoxide and hydroxyl radical scavenging. Polyphenols showed a dose?response relationship (R2 > 0.90) with antioxidant capacity in the decoction and the alcoholic beverage. The maceration showed an inhibitory effect on lipoxygenase (LOX) activity with an inhibitory concentration (IC50) value of 183.80 μg gallic acid equivalents (GAE)/mL but the decoction did not. On the other hand, extracts did not show any mutagenic effect. Therefore, mistol fruits consumption could be encouraged not only for its functional properties, but also because of the positive ecological impact of preserving biological diversity through the exploitation of native natural resources in a regional economy.
Palabras clave:
Biological Activity
,
Genotoxicity
,
Ziziphus Mistol
Archivos asociados
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Identificadores
Colecciones
Articulos(INQUINOA)
Articulos de INST.DE QUIMICA DEL NOROESTE
Articulos de INST.DE QUIMICA DEL NOROESTE
Citación
Cardozo, María Luz; Ordóñez, Roxana Mabel; Alberto, Maria Rosa; Zampini, Iris Catiana; Isla, Maria Ines; Antioxidant and anti-inflammatory activity characterization and genotoxicity evaluation of Ziziphus mistol ripe berries, exotic Argentinean fruit; Elsevier Science; Food Research International; 44; 7; 8-2011; 2063-2071
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