Artículo

Bioactive Sesqui- and Diterpenoids from the Argentine Liverwort Porella chilensis

Gilabert Valero, José MiguelIcon ; Ramos Vernieri, Alberto NicolásIcon ; Schiavone, Maria Magdalena; Arena, Mario EduardoIcon ; Bardon, Alicia del ValleIcon
Fecha de publicación: 04/2011
Editorial: American Chemical Society
Revista: Journal of Natural Products
ISSN: 0163-3864
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Four fusicoccane-type diterpenoids (1−4), including the new 1 and 2; four pinguisane-type sesquiterpenoids (5−8); and two aromadendrane-type sesquiterpenoids (9 and 10) were isolated from an Argentine collection of the endemic liverwort Porella chilensis. The biofilm formation of the human pathogen Pseudomonas aeruginosa was inhibited by compounds 3 (53 and 47%), 9 (45 and 41%), and 10 (48 and 37%) at 50 and 5 μg/mL, respectively. Compounds 3, 9, and 10 also produced a slight decrease in bacterial growth and interfere with the process of quorum sensing at the same doses.
Palabras clave: Porella Chilensis , Biofilm Formation , Fusicoccane-Type Diterpenoids , Quorum Sensing
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/51926
DOI: https://dx.doi.org/10.1021/np100472d
URL: https://pubs.acs.org/doi/abs/10.1021/np100472d
Colecciones
Articulos(INQUINOA)
Articulos de INST.DE QUIMICA DEL NOROESTE
Citación
Gilabert Valero, José Miguel; Ramos Vernieri, Alberto Nicolás; Schiavone, Maria Magdalena; Arena, Mario Eduardo; Bardon, Alicia del Valle; Bioactive Sesqui- and Diterpenoids from the Argentine Liverwort Porella chilensis; American Chemical Society; Journal of Natural Products; 74; 4; 4-2011; 574-579
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