Artículo

Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination

Tan, Eric; Konovalov, Andrey I.; Fernandez, Gabriela AraceliIcon ; Dorel, Ruth; Echavarren, Antonio M.
Fecha de publicación: 10/2017
Editorial: American Chemical Society
Revista: Organic Letters
ISSN: 1523-7060
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The alkynylation of naphthols takes place with total regiocontrol at the peri position of the hydroxyl group in the presence of [RuCl2(p-cymene)]2 as the catalyst. This reaction features high functional group tolerance. The related ortho-alkynylation of benzoic acids proceeds under similar conditions and also shows wide functional group tolerance. Both reactions proceed through metalation, insertion of the alkyne, and bromide elimination.
Palabras clave: Ruthenium Catalyst , Alkynylation , Naphtols , Benzoic Acids
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
URI: http://hdl.handle.net/11336/50324
URL: http://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b02655
DOI: http://dx.doi.org/10.1021/acs.orglett.7b02655
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679662/
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Articulos(CIBION)
Articulos de CENTRO DE INVESTIGACIONES EN BIONANOCIENCIAS "ELIZABETH JARES ERIJMAN"
Citación
Tan, Eric; Konovalov, Andrey I.; Fernandez, Gabriela Araceli; Dorel, Ruth; Echavarren, Antonio M.; Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination; American Chemical Society; Organic Letters; 19; 20; 10-2017; 5561-5564
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