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dc.contributor.author
Romero, Ester
dc.contributor.author
Holtzman, Jessica N.
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Tannenhaus, Lucila
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Monchablon, Romina
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Rago, Carlo Mario
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Lolich, Maria
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dc.contributor.author
Vázquez, Gustavo H.
dc.date.available
2018-04-27T19:38:02Z
dc.date.issued
2016-04
dc.identifier.citation
Romero, Ester; Holtzman, Jessica N.; Tannenhaus, Lucila; Monchablon, Romina; Rago, Carlo Mario; et al.; Neuropsychological performance and affective temperaments in Euthymic patients with bipolar disorder type II; Elsevier Ireland; Psychiatry Research; 238; 4-2016; 172-180
dc.identifier.issn
0165-1781
dc.identifier.uri
http://hdl.handle.net/11336/43728
dc.description.abstract
Affective temperament has been suggested as a potential mediator of the effect between genetic predisposition and neurocognitive functioning. As such, this report seeks to assess the extent of the correlation between affective temperament and cognitive function in a group of bipolar II subjects. 46 bipolar II outpatients [mean age 41.4 years (SD 18.2); female 58.9%] and 46 healthy controls [mean age 35.1 years (SD 18); female 56.5%] were evaluated with regard to their demographic and clinical characteristics, affective temperament, and neurocognitive performance. Crude bivariate correlation analyses and multiple linear regression models were constructed between five affective temperament subscales and eight neurocognitive domains. Significant correlations were identified in bipolar patients between hyperthymic temperament and verbal memory and premorbid IQ; cyclothymic temperament and attention; and irritable temperament, attention, and verbal fluency. In adjusting for potential confounders of the relationship between temperament and cognitive function, the strongest mediating factors among the euthymic bipolar patients were found to be residual manic and depressive symptoms. It is therefore concluded that affective temperaments may partially influence the neurocognitive performance of both healthy controls and euthymic patients with bipolar disorder type II in several specific domains.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Ireland
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Temperamental Traits
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Euthymia
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Neurocognition
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Affective Disorder
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Subsyndromal Symptoms
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Endophenotypes
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Verbal Memory
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Visual Memory
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Planning
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Set Shifting
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Attention
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Working Memory
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Processing Speed
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Verbal Fluency
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Premorbid Iq
dc.subject.classification
Salud Ocupacional
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Neuropsychological performance and affective temperaments in Euthymic patients with bipolar disorder type II
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-04-27T13:59:26Z
dc.journal.volume
238
dc.journal.pagination
172-180
dc.journal.pais
Irlanda
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dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Romero, Ester. Universidad de Palermo; Argentina
dc.description.fil
Fil: Holtzman, Jessica N.. Universidad de Palermo; Argentina. University of Stanford; Estados Unidos
dc.description.fil
Fil: Tannenhaus, Lucila. Universidad de Palermo; Argentina
dc.description.fil
Fil: Monchablon, Romina. Universidad de Palermo; Argentina
dc.description.fil
Fil: Rago, Carlo Mario. Universidad de Palermo; Argentina. Instituto de Investigaciones Universitarias Roma la Sapienza; Italia
dc.description.fil
Fil: Lolich, Maria. Universidad de Palermo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Vázquez, Gustavo H.. Universidad de Palermo; Argentina. McLean Hospital; Estados Unidos
dc.journal.title
Psychiatry Research
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.psychres.2016.02.032
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165178115305345
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