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dc.contributor.author
Celaya, Liliana Soledad
dc.contributor.author
Viturro, Carmen Ines
dc.contributor.author
Rodriguez Silva, Luis
dc.date.available
2018-04-18T17:20:22Z
dc.date.issued
2017-04
dc.identifier.citation
Celaya, Liliana Soledad; Viturro, Carmen Ines; Rodriguez Silva, Luis; Chemical Composition and Biological Prospects of Essential Oils and Extracts of Aphyllocladus spartioides Growing in Northwest Argentina; Wiley VCH Verlag; Chemistry and Biodiversity; 14; 4; 4-2017; 1-10; e1600227
dc.identifier.issn
1612-1872
dc.identifier.uri
http://hdl.handle.net/11336/42489
dc.description.abstract
Aphyllocladus spartioides WEDD. is a native and aromatic herb used in traditional medicine, however it is still poorly investigated. In this work, the volatile profile of A. spartioides growing in Hornillos-Northwest Argentina was determined by GC/MS/FID and the phenolic compounds of hydroethanolic and decoction extracts were analyzed by HPLC-DAD. The antibacterial potential, antioxidant activity and α‐glucosidase inhibition activity were checked by in vitro assays. The volatile profile allowed the identification of 68 compounds, being α‐pinene and cadinene the main ones. Eighteen phenolics were identified, isorhamnetin derivatives and different phenolic acid derivatives were found in higher amounts, mainly in the hydroethanolic extract. A concentration-dependent activity was noticed against DPPH , O2, NO and α‐glucosidase, these activities being reported for the first time. Hydroethanolic extract was most active against DPPH , NO and α‐glucosidase (IC50 = 79, 206 and 181 lg/ml). Decoction extract proved to be better against O2 (IC50 = 20 lg/ml). Regarding the antibacterial activity, hydroethanolic extract was more active compared with decoction and essential oil. MICs of 0.3 – 0.6 mg/ml were obtained against Staphylococcus aureus, Bacillus cereus, and Micrococcus luteus. Results suggest that the extracts of A. spartioides from Northwest Argentina may be interesting to use as a source of natural antioxidants/antimicrobials for pharmaceutical incorporations or food supplementation.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley VCH Verlag
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Aphyllocladus Spartioides
dc.subject
Bioactive Compounds
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Essentail Oils
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Polar Extracts
dc.subject.classification
Otras Ciencias Químicas
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Chemical Composition and Biological Prospects of Essential Oils and Extracts of Aphyllocladus spartioides Growing in Northwest Argentina
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-04-16T13:38:47Z
dc.identifier.eissn
1612-1880
dc.journal.volume
14
dc.journal.number
4
dc.journal.pagination
1-10; e1600227
dc.journal.pais
Alemania
dc.journal.ciudad
Weinheim
dc.description.fil
Fil: Celaya, Liliana Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Jujuy. Universidad Nacional de Jujuy. Centro de Investigaciones y Transferencia de Jujuy; Argentina. Universidad de Porto; Portugal
dc.description.fil
Fil: Viturro, Carmen Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Jujuy. Universidad Nacional de Jujuy. Centro de Investigaciones y Transferencia de Jujuy; Argentina
dc.description.fil
Fil: Rodriguez Silva, Luis. Universidad de Porto; Portugal
dc.journal.title
Chemistry and Biodiversity
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.201600227
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1002/cbdv.201600227
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