Artículo
Tissue alkalosis in cold-ischemia time
Denninghoff, Valeria Cecilia
; Olivieri, E. H. R.; Fresno Rodríguez, Cristóbal
; Uceda, Ana Margarita; Mota, L.; Suenaga, A. P.; Carraro, D. M.; Martins, V. R.; Avagnina, Alejandra; Soares, F. A.; Campos, A. H. J. Fróes Marques
Fecha de publicación:
12/2017
Editorial:
Nature Publishing Group
Revista:
Scientific Reports
ISSN:
2045-2322
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The control of pre-Analytical-factors in human biospecimens collected for health research is currently required. Only two previous reports using post-mortem brain samples have tried to address the impact of cold-ischemia on tissue pH. Here we report pH variations according to time (third-order polynomial model) in mice for liver, kidney and lung samples. Tissue alkalosis in cold-ischemia time may be an underlying mechanism of gene expression changes. Therefore, tissue-pH regulation after organ removal may minimize biological stress in human tissue samples.
Palabras clave:
Ischemia
,
Alkalosis
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CEMIC-CONICET)
Articulos de CENTRO DE EDUCACION MEDICA E INVESTIGACIONES CLINICAS "NORBERTO QUIRNO"
Articulos de CENTRO DE EDUCACION MEDICA E INVESTIGACIONES CLINICAS "NORBERTO QUIRNO"
Citación
Denninghoff, Valeria Cecilia; Olivieri, E. H. R.; Fresno Rodríguez, Cristóbal; Uceda, Ana Margarita; Mota, L.; et al.; Tissue alkalosis in cold-ischemia time; Nature Publishing Group; Scientific Reports; 7; 1; 12-2017; 1-6; 10867
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