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dc.contributor.author
Houshmandi, S.S.  
dc.contributor.author
Surace, Ezequiel Ignacio  
dc.contributor.author
Zhang, H.B.  
dc.contributor.author
Fuller, G.N.  
dc.contributor.author
Gutmann, D.H.  
dc.date.available
2018-03-16T13:57:59Z  
dc.date.issued
2006-11  
dc.identifier.citation
Houshmandi, S.S.; Surace, Ezequiel Ignacio; Zhang, H.B.; Fuller, G.N.; Gutmann, D.H.; Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor; Lippincott Williams; Neurology; 67; 10; 11-2006; 1863-1866  
dc.identifier.issn
0028-3878  
dc.identifier.uri
http://hdl.handle.net/11336/39064  
dc.description.abstract
Tumor suppressor in lung cancer-1 (TSLC1) loss is common in many human cancers, including meningioma. In this study, we demonstrate that TSLC1 protein and RNA expression is lost in 60% to 65% of high-grade gliomas, and that TSLC1 reintroduction into glioma cells results in growth suppression. Moreover, Tslc1 loss in mice results in increased astrocyte proliferation in vivo and in vitro. These data indicate that TSLC1 functions as a glioma tumor suppressor. ©2006AAN Enterprises, Inc.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Lippincott Williams  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Lung Cancer  
dc.subject
Tumor Suppressor  
dc.subject.classification
Otras Ciencias Biológicas  
dc.subject.classification
Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-03-15T15:21:57Z  
dc.identifier.eissn
1526-632X  
dc.journal.volume
67  
dc.journal.number
10  
dc.journal.pagination
1863-1866  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Philadelphia  
dc.description.fil
Fil: Houshmandi, S.S.. Washington University in St. Louis; Estados Unidos  
dc.description.fil
Fil: Surace, Ezequiel Ignacio. Washington University in St. Louis; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina  
dc.description.fil
Fil: Zhang, H.B.. Washington University in St. Louis; Estados Unidos  
dc.description.fil
Fil: Fuller, G.N.. University of Texas; Estados Unidos  
dc.description.fil
Fil: Gutmann, D.H.. Washington University in St. Louis; Estados Unidos  
dc.journal.title
Neurology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://n.neurology.org/content/67/10/1863.long  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1212/01.wnl.0000244472.56198.84  

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