Artículo

Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor

Houshmandi, S.S.; Surace, Ezequiel IgnacioIcon ; Zhang, H.B.; Fuller, G.N.; Gutmann, D.H.
Fecha de publicación: 11/2006
Editorial: Lippincott Williams
Revista: Neurology
ISSN: 0028-3878
e-ISSN: 1526-632X
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Tumor suppressor in lung cancer-1 (TSLC1) loss is common in many human cancers, including meningioma. In this study, we demonstrate that TSLC1 protein and RNA expression is lost in 60% to 65% of high-grade gliomas, and that TSLC1 reintroduction into glioma cells results in growth suppression. Moreover, Tslc1 loss in mice results in increased astrocyte proliferation in vivo and in vitro. These data indicate that TSLC1 functions as a glioma tumor suppressor. ©2006AAN Enterprises, Inc.
Palabras clave: Lung Cancer , Tumor Suppressor
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/39064
URL: http://n.neurology.org/content/67/10/1863.long
DOI: http://dx.doi.org/10.1212/01.wnl.0000244472.56198.84
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Articulos(IIBBA)
Articulos de INST.DE INVEST.BIOQUIMICAS DE BS.AS(I)
Citación
Houshmandi, S.S.; Surace, Ezequiel Ignacio; Zhang, H.B.; Fuller, G.N.; Gutmann, D.H.; Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor; Lippincott Williams; Neurology; 67; 10; 11-2006; 1863-1866
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