Artículo
Cholinergic transmission underlies modulation of frustration by open field exposure
Fecha de publicación:
01/2016
Editorial:
Pergamon-Elsevier Science Ltd
Revista:
Pharmacology Biochemistry and Behavior
ISSN:
0091-3057
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Frustration can be defined as an emotional state generated by the omission or devaluation in the quantity or quality of an expected appetitive reward. Thus, reactivity to a reward is affected by prior experience with the different reinforcer values of that reward. This phenomenon is known as incentive relativity, and can be studied by different paradigms. Although methodologically simple, the exploration of a novel open field (OF) is a complex situation that involves several behavioral processes, including stress induction and novelty detection. OF exposure can enhance or block the acquisition of associative and nonassociative memories. These experiments evaluated the effect of OF exploration on frustration and the role played by the cholinergic systemin this phenomenon. OF exploration before first or second trial of incentive downshift modulated the expression of frustration. This effect of OF was blocked by the administration of scopolamine either before or after OF exploration. These results indicate that the cholinergic system is involved in the acquisition and consolidation of OF information.
Palabras clave:
CHOLINERGIC SYSTEM
,
FRUSTRATION
,
MEMORY
,
NOVELTY
,
OPEN FIELD
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Identificadores
Colecciones
Articulos(IDIM)
Articulos de INST.DE INVEST.MEDICAS
Articulos de INST.DE INVEST.MEDICAS
Articulos(INIMEC - CONICET)
Articulos de INSTITUTO DE INV. MEDICAS MERCEDES Y MARTIN FERREYRA
Articulos de INSTITUTO DE INV. MEDICAS MERCEDES Y MARTIN FERREYRA
Citación
Psyrdellis, Mariana; Pautassi, Ricardo Marcos; Mustaca, Alba Elisabeth; Justel, Nadia; Cholinergic transmission underlies modulation of frustration by open field exposure; Pergamon-Elsevier Science Ltd; Pharmacology Biochemistry and Behavior; 140; 1-2016; 8-16
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