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dc.contributor.author
Psyrdellis, Mariana
dc.contributor.author
Pautassi, Ricardo Marcos
dc.contributor.author
Mustaca, Alba Elisabeth
dc.contributor.author
Justel, Nadia
dc.date.available
2018-03-14T20:59:02Z
dc.date.issued
2016-01
dc.identifier.citation
Psyrdellis, Mariana; Pautassi, Ricardo Marcos; Mustaca, Alba Elisabeth; Justel, Nadia; Cholinergic transmission underlies modulation of frustration by open field exposure; Pergamon-Elsevier Science Ltd; Pharmacology Biochemistry and Behavior; 140; 1-2016; 8-16
dc.identifier.issn
0091-3057
dc.identifier.uri
http://hdl.handle.net/11336/38837
dc.description.abstract
Frustration can be defined as an emotional state generated by the omission or devaluation in the quantity or quality of an expected appetitive reward. Thus, reactivity to a reward is affected by prior experience with the different reinforcer values of that reward. This phenomenon is known as incentive relativity, and can be studied by different paradigms. Although methodologically simple, the exploration of a novel open field (OF) is a complex situation that involves several behavioral processes, including stress induction and novelty detection. OF exposure can enhance or block the acquisition of associative and nonassociative memories. These experiments evaluated the effect of OF exploration on frustration and the role played by the cholinergic systemin this phenomenon. OF exploration before first or second trial of incentive downshift modulated the expression of frustration. This effect of OF was blocked by the administration of scopolamine either before or after OF exploration. These results indicate that the cholinergic system is involved in the acquisition and consolidation of OF information.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Pergamon-Elsevier Science Ltd
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
CHOLINERGIC SYSTEM
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FRUSTRATION
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MEMORY
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NOVELTY
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OPEN FIELD
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Psicología
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Psicología
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CIENCIAS SOCIALES
dc.title
Cholinergic transmission underlies modulation of frustration by open field exposure
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-14T17:04:35Z
dc.journal.volume
140
dc.journal.pagination
8-16
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Psyrdellis, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
dc.description.fil
Fil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
dc.description.fil
Fil: Mustaca, Alba Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Universidad Abierta Interamericana; Argentina
dc.description.fil
Fil: Justel, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
dc.journal.title
Pharmacology Biochemistry and Behavior
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.pbb.2015.10.017
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0091305715300903