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dc.contributor.author
José, Carla  
dc.contributor.author
Briand, Laura Estefania  
dc.date.available
2015-12-17T18:42:00Z  
dc.date.issued
2010-02  
dc.identifier.citation
José, Carla; Briand, Laura Estefania; Deactivation of Novozym® 435 during the esterification of ibuprofen with ethanol: Evidences of the detrimental effect of the alcohol; Springer; Reaction Kinetics, Mechanisms and Catalysis; 99; 1; 2-2010; 17-22  
dc.identifier.issn
1878-5190  
dc.identifier.uri
http://hdl.handle.net/11336/3016  
dc.description.abstract
The stability of Novozym® 435 in the esterification of ibuprofen using ethanol as reactant and solvent was investigated. Additionally, the surface interaction of the isomers of ibuprofen and ethanol with the biocatalyst was screened through conventional adsorption isotherms and temperature programmed surface reaction (TPSR). These investigations evidenced strong alcohol adsorption and dissolution of the biocatalyst, which explains its deactivation upon reuses in the esterification reaction.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Ethanol  
dc.subject
Ibuprofen  
dc.subject
Novozym 435  
dc.subject
Biocatalyst  
dc.subject.classification
Bioprocesamiento Tecnológico, Biocatálisis, Fermentación  
dc.subject.classification
Biotecnología Industrial  
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS  
dc.title
Deactivation of Novozym® 435 during the esterification of ibuprofen with ethanol: Evidences of the detrimental effect of the alcohol  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2016-03-30 10:35:44.97925-03  
dc.identifier.eissn
1588-2837  
dc.journal.volume
99  
dc.journal.number
1  
dc.journal.pagination
17-22  
dc.journal.pais
Alemania  
dc.journal.ciudad
Berlín  
dc.description.fil
Fil: José, Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina  
dc.description.fil
Fil: Briand, Laura Estefania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina  
dc.journal.title
Reaction Kinetics, Mechanisms and Catalysis  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s11144-009-0103-4  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s11144-009-0103-4  

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