Artículo

Deactivation of Novozym® 435 during the esterification of ibuprofen with ethanol: Evidences of the detrimental effect of the alcohol

José, CarlaIcon ; Briand, Laura EstefaniaIcon
Fecha de publicación: 02/2010
Editorial: Springer
Revista: Reaction Kinetics, Mechanisms and Catalysis
ISSN: 1878-5190
e-ISSN: 1588-2837
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The stability of Novozym® 435 in the esterification of ibuprofen using ethanol as reactant and solvent was investigated. Additionally, the surface interaction of the isomers of ibuprofen and ethanol with the biocatalyst was screened through conventional adsorption isotherms and temperature programmed surface reaction (TPSR). These investigations evidenced strong alcohol adsorption and dissolution of the biocatalyst, which explains its deactivation upon reuses in the esterification reaction.
Palabras clave: Ethanol , Ibuprofen , Novozym 435 , Biocatalyst
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/3016
URL: https://link.springer.com/article/10.1007/s11144-009-0103-4
DOI: http://dx.doi.org/10.1007/s11144-009-0103-4
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Articulos(CINDECA)
Articulos de CENTRO DE INV EN CS.APLICADAS "DR.JORGE J.RONCO"
Citación
José, Carla; Briand, Laura Estefania; Deactivation of Novozym® 435 during the esterification of ibuprofen with ethanol: Evidences of the detrimental effect of the alcohol; Springer; Reaction Kinetics, Mechanisms and Catalysis; 99; 1; 2-2010; 17-22
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