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dc.contributor.author
Llères, David  
dc.contributor.author
Cardozo Gizzi, Andres Mauricio  
dc.contributor.author
Nollmann, Marcelo  
dc.date.available
2025-09-15T14:55:40Z  
dc.date.issued
2025-08  
dc.identifier.citation
Llères, David; Cardozo Gizzi, Andres Mauricio; Nollmann, Marcelo; Redefining enhancer action: Insights from structural, genomic, and single-molecule perspectives; Current Biology; Current Opinion In Cell Biology; 95; 8-2025; 1-11  
dc.identifier.issn
0955-0674  
dc.identifier.uri
http://hdl.handle.net/11336/271013  
dc.description.abstract
This review explores recent emerging insights into enhanceraction, focusing on underexplored aspects such as the phys-ical size of regulatory elements, the stochasticity of transcrip-tion factor binding and chromatin structure, and the role ofnonlinear processes in reconciling longstanding discrepanciesbetween theoretical models and experimental observations.Together, these insights provide a nuanced view of enhancerbiology, highlighting the complexity of gene regulation and theneed for innovative methodologies to further decode enhancermechanisms.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Current Biology  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc/2.5/ar/  
dc.subject
ENHANCER-PROMOTER INTERACTION  
dc.subject
CHROMATIN STRUCTURE  
dc.subject
TRANSCRIPTIONAL REGULATION  
dc.subject.classification
Bioquímica y Biología Molecular  
dc.subject.classification
Medicina Básica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Redefining enhancer action: Insights from structural, genomic, and single-molecule perspectives  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2025-09-11T12:11:16Z  
dc.journal.volume
95  
dc.journal.pagination
1-11  
dc.journal.pais
Países Bajos  
dc.description.fil
Fil: Llères, David. Université Montpellier II; Francia  
dc.description.fil
Fil: Cardozo Gizzi, Andres Mauricio. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina  
dc.description.fil
Fil: Nollmann, Marcelo. Université Montpellier II; Francia  
dc.journal.title
Current Opinion In Cell Biology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0955067425000651  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ceb.2025.102527  

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