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dc.contributor.author
Chiappini, Fabricio Alejandro  
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Teglia, Carla Mariela  
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Azcarate, Silvana Mariela  
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Goicoechea, Hector Casimiro  
dc.contributor.other
Breitkreitz, Márcia Cristina  
dc.contributor.other
Goicoechea, Hector Casimiro  
dc.date.available
2024-10-29T12:02:47Z  
dc.date.issued
2023  
dc.identifier.citation
Chiappini, Fabricio Alejandro; Teglia, Carla Mariela; Azcarate, Silvana Mariela; Goicoechea, Hector Casimiro; Fundamentals of Design of Experiments and Optimization: Designs for Factor Screening and Data Analysis in Pre-Response Surface Methodology; Springer; 2023; 29-45  
dc.identifier.isbn
978-3-031-31504-6  
dc.identifier.uri
http://hdl.handle.net/11336/246680  
dc.description.abstract
Chapter 2 presents an overview of the most important designs implemented for factor screening, including data analysis in pre-response surface methodology (pre-RSM). This chapter mainly focuses on practical aspects consid-ering a group of experimental factors at different levels at the same time, with a minimum number of experiments. Then it is discussed how to carry out studies in order to build an empirical model that correlates the information about factors and responses. Data analysis in pre-RSM is mostly represented by the well-known statistical method of multiway analysis of variance (ANOVA), whose basics are presented, together with the analysis of the validity of the results. In addition, two graphical strategies, the Pareto chart and the diagram of normal probability, are discussed. An example is used to illustrate the concepts. Suitable references are provided.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
FACTOR SCREENING  
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PRE-RESPONSE SURFACE METHODOLOGY  
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DESIGN OF EXPERIMENTS  
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MULTIVARIATE OPTIMIZATION  
dc.subject.classification
Química Analítica  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Fundamentals of Design of Experiments and Optimization: Designs for Factor Screening and Data Analysis in Pre-Response Surface Methodology  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/bookPart  
dc.type
info:ar-repo/semantics/parte de libro  
dc.date.updated
2024-10-29T11:50:54Z  
dc.journal.pagination
29-45  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Chiappini, Fabricio Alejandro. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Desarrollo Analítico y Quimiometría; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina  
dc.description.fil
Fil: Teglia, Carla Mariela. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Desarrollo Analítico y Quimiometría; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina  
dc.description.fil
Fil: Azcarate, Silvana Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ciencias de la Tierra y Ambientales de La Pampa. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales. Instituto de Ciencias de la Tierra y Ambientales de La Pampa; Argentina  
dc.description.fil
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Desarrollo Analítico y Quimiometría; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/chapter/10.1007/978-3-031-31505-3_2  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/978-3-031-31505-3_2  
dc.conicet.paginas
266  
dc.source.titulo
Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development