Capítulo de Libro
Fundamentals of Design of Experiments and Optimization: Designs for Factor Screening and Data Analysis in Pre-Response Surface Methodology
Título del libro: Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development
Chiappini, Fabricio Alejandro
; Teglia, Carla Mariela
; Azcarate, Silvana Mariela
; Goicoechea, Hector Casimiro
Fecha de publicación:
2023
Editorial:
Springer
ISBN:
978-3-031-31504-6
Idioma:
Inglés
Clasificación temática:
Resumen
Chapter 2 presents an overview of the most important designs implemented for factor screening, including data analysis in pre-response surface methodology (pre-RSM). This chapter mainly focuses on practical aspects consid-ering a group of experimental factors at different levels at the same time, with a minimum number of experiments. Then it is discussed how to carry out studies in order to build an empirical model that correlates the information about factors and responses. Data analysis in pre-RSM is mostly represented by the well-known statistical method of multiway analysis of variance (ANOVA), whose basics are presented, together with the analysis of the validity of the results. In addition, two graphical strategies, the Pareto chart and the diagram of normal probability, are discussed. An example is used to illustrate the concepts. Suitable references are provided.
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Capítulos de libros(CCT - SANTA FE)
Capítulos de libros de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Capítulos de libros de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Capítulos de libros(INCITAP)
Capítulos de libros de INST.D/CS D/L/TIERRA Y AMBIENTALES D/L/PAMPA
Capítulos de libros de INST.D/CS D/L/TIERRA Y AMBIENTALES D/L/PAMPA
Citación
Chiappini, Fabricio Alejandro; Teglia, Carla Mariela; Azcarate, Silvana Mariela; Goicoechea, Hector Casimiro; Fundamentals of Design of Experiments and Optimization: Designs for Factor Screening and Data Analysis in Pre-Response Surface Methodology; Springer; 2023; 29-45
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