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dc.contributor.author
Trelles, Jorge Abel  
dc.contributor.author
Valino, Ana Laura  
dc.contributor.author
Runza, V.  
dc.contributor.author
Lewkowicz, Elizabeth Sandra  
dc.contributor.author
Iribarren, Adolfo Marcelo  
dc.date.available
2024-09-13T13:18:37Z  
dc.date.issued
2005-06  
dc.identifier.citation
Trelles, Jorge Abel; Valino, Ana Laura; Runza, V.; Lewkowicz, Elizabeth Sandra; Iribarren, Adolfo Marcelo; Screening of Catalytically Active Microorganisms for the Synthesis of 6-Modified Purine Nucleosides; Springer; Biotechnology Letters; 27; 11; 6-2005; 759-763  
dc.identifier.issn
0141-5492  
dc.identifier.uri
http://hdl.handle.net/11336/244236  
dc.description.abstract
Modified nucleosides can be prepared by microbial transglycosylation from cheaper nucleoside precursors using free or immobilised whole cells. An efficient screening method to find transglycosylation activity in microorganisms was developed for the synthesis of 6-modified purine nucleosides, such as 6-chloro-, 6-methoxy-, 6-iodo- and 6-mercaptopurine ribonucleoside. Out of 100 microorganisms screened, Bacillus stearothermophilus (ATCC 12980) was found to be the best strain for this purpose.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
NUCLEOSIDES  
dc.subject
TRANSGLYCOSYLATION  
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MICROORGANISMS  
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RIBONUCLEOSIDES  
dc.subject.classification
Química Orgánica  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Screening of Catalytically Active Microorganisms for the Synthesis of 6-Modified Purine Nucleosides  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2024-09-13T11:35:05Z  
dc.journal.volume
27  
dc.journal.number
11  
dc.journal.pagination
759-763  
dc.journal.pais
Alemania  
dc.journal.ciudad
Berlín  
dc.description.fil
Fil: Trelles, Jorge Abel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina  
dc.description.fil
Fil: Valino, Ana Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina  
dc.description.fil
Fil: Runza, V.. Universidad Nacional de Quilmes; Argentina  
dc.description.fil
Fil: Lewkowicz, Elizabeth Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina  
dc.description.fil
Fil: Iribarren, Adolfo Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina. Universidad Nacional de Quilmes; Argentina  
dc.journal.title
Biotechnology Letters  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s10529-005-5628-7  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s10529-005-5628-7  

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