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dc.contributor.author
Lopes Pinto, Mariana  
dc.contributor.author
Lunet Marques, Patrícia  
dc.contributor.author
Lacerda Nobre, Ema  
dc.contributor.author
Miceli, Diego Daniel  
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Oliveira Leal, Rodolfo  
dc.contributor.author
Marques, Pedro  
dc.date.available
2024-08-19T11:47:31Z  
dc.date.issued
2024-06  
dc.identifier.citation
Lopes Pinto, Mariana; Lunet Marques, Patrícia; Lacerda Nobre, Ema; Miceli, Diego Daniel; Oliveira Leal, Rodolfo; et al.; Acromegaly in humans and cats: pathophysiological, clinical and management resemblances and differences; Elsevier; Growth Hormone & IGF Research; 76; 101595; 6-2024; 1-11  
dc.identifier.issn
1096-6374  
dc.identifier.uri
http://hdl.handle.net/11336/242713  
dc.description.abstract
Acromegaly is a disorder associated with excessive levels of growth hormone (GH) and insulin-like growth factor-1 (IGF-1). In general, GH/IGF-1 excess leads to morphologic craniofacial and acral changes as well as cardiometabolic complications, but the phenotypic changes and clinical presentation of acromegaly differ across species. Here, we review the pathophysiology, clinical presentation and management of acromegaly in humans and cats, and we provide a systematic comparison between this disease across these different species.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/  
dc.subject
ACROMEGALY  
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GIGANTISM  
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GROWTH HORMONE  
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INSULIN-LIKE GROWTH FACTOR 1  
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Ciencias Veterinarias  
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Ciencias Veterinarias  
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CIENCIAS AGRÍCOLAS  
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Endocrinología y Metabolismo  
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Medicina Clínica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Acromegaly in humans and cats: pathophysiological, clinical and management resemblances and differences  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2024-08-12T15:06:22Z  
dc.identifier.eissn
1532-2238  
dc.journal.volume
76  
dc.journal.number
101595  
dc.journal.pagination
1-11  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Lopes Pinto, Mariana. Unidade Local de Saúde de Santa María; Portugal  
dc.description.fil
Fil: Lunet Marques, Patrícia. Universidade de Lisboa. Faculty of Veterinary Medicine. Centre for Interdisciplinary Research in Animal Health ; Portugal. Associate Laboratory for Animal and Veterinary Sciences; Portugal  
dc.description.fil
Fil: Lacerda Nobre, Ema. Unidade Local de Saúde de Santa María; Portugal  
dc.description.fil
Fil: Miceli, Diego Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina  
dc.description.fil
Fil: Oliveira Leal, Rodolfo. Universidade de Lisboa. Faculty of Veterinary Medicine. Centre for Interdisciplinary Research in Animal Health ; Portugal. Associate Laboratory for Animal and Veterinary Sciences; Portugal  
dc.description.fil
Fil: Marques, Pedro. Hospital CUF Descorbetas; Portugal. Universidade Católica Portuguesa; Portugal  
dc.journal.title
Growth Hormone & IGF Research  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S109663742400025X  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ghir.2024.101595  

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