Artículo
Acromegaly in humans and cats: pathophysiological, clinical and management resemblances and differences
Lopes Pinto, Mariana; Lunet Marques, Patrícia; Lacerda Nobre, Ema; Miceli, Diego Daniel
; Oliveira Leal, Rodolfo; Marques, Pedro
Fecha de publicación:
06/2024
Editorial:
Elsevier
Revista:
Growth Hormone & IGF Research
ISSN:
1096-6374
e-ISSN:
1532-2238
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Acromegaly is a disorder associated with excessive levels of growth hormone (GH) and insulin-like growth factor-1 (IGF-1). In general, GH/IGF-1 excess leads to morphologic craniofacial and acral changes as well as cardiometabolic complications, but the phenotypic changes and clinical presentation of acromegaly differ across species. Here, we review the pathophysiology, clinical presentation and management of acromegaly in humans and cats, and we provide a systematic comparison between this disease across these different species.
Palabras clave:
ACROMEGALY
,
GIGANTISM
,
GROWTH HORMONE
,
INSULIN-LIKE GROWTH FACTOR 1
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Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Lopes Pinto, Mariana; Lunet Marques, Patrícia; Lacerda Nobre, Ema; Miceli, Diego Daniel; Oliveira Leal, Rodolfo; et al.; Acromegaly in humans and cats: pathophysiological, clinical and management resemblances and differences; Elsevier; Growth Hormone & IGF Research; 76; 101595; 6-2024; 1-11
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