Artículo
Lab-on-a-bead: Polymeric natural deep eutectic solvents as a versatile platform for (bio)sensor design
Gomez, Federico Jose Vicente
; Vidal, Ezequiel Martin; Domini, Claudia Elizabeth
; Zanini, Graciela Pilar
; Silva, María Fernanda
; Garcia, Carlos D.
![Icon](/themes/CONICETDigital/images/conicet.png)
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Fecha de publicación:
08/2023
Editorial:
Elsevier Science
Revista:
Journal of Molecular Liquids
ISSN:
0167-7322
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Natural polymers offer not only low-cost, wide availability, biocompatibility, and biodegradability but also a rich chemical functionality towards custom modifications and new applications. Among those, sodium alginate (ALG) offers several competitive advantages, including the possibility to form beads by a simple process call spherification as well as their modification by a wide number of processes, including the possibility to mixing the alginate solution with deep eutectic solvents (DES). Thus, and considering the capacity of DES to stabilize enzymes, the main objective of this work was to design and fabricate a new polymeric DES (using ALG as one of the components, ALGPODES) and to deploy this material as a new phase to develop colorimetric biosensors. The formed beads displayed a narrow size distribution (2.9 ± 0.1 mm) and a permeable structure with large internal cavities (25–100 µm). The applicability of these beads towards analytical applications (lab-on-a-bead) was demonstrated by integrating three sensing platforms and by their application in real food samples.
Palabras clave:
eutectic solvents
,
Alginate
,
beads
,
biosensor
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Articulos(IBAM)
Articulos de INST.DE BIOLOGIA AGRICOLA DE MENDOZA
Articulos de INST.DE BIOLOGIA AGRICOLA DE MENDOZA
Articulos(INQUISUR)
Articulos de INST.DE QUIMICA DEL SUR
Articulos de INST.DE QUIMICA DEL SUR
Citación
Gomez, Federico Jose Vicente; Vidal, Ezequiel Martin; Domini, Claudia Elizabeth; Zanini, Graciela Pilar; Silva, María Fernanda; et al.; Lab-on-a-bead: Polymeric natural deep eutectic solvents as a versatile platform for (bio)sensor design; Elsevier Science; Journal of Molecular Liquids; 383; 8-2023; 1-9
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