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dc.contributor.author
Corvalán Moya, Carolina del Huerto
dc.contributor.author
Vega, Daniel Roberto
dc.date.available
2017-09-07T18:39:52Z
dc.date.issued
2013-11
dc.identifier.citation
Corvalán Moya, Carolina del Huerto; Vega, Daniel Roberto; Venlafaxine besylate monohydrate; International Union of Crystallography; Acta Crystallographica Section E: Crystallographic Communications; 69; 11-2013; 1737-1738
dc.identifier.issn
2056-9890
dc.identifier.uri
http://hdl.handle.net/11336/23787
dc.description.abstract
The title compound {systematic name: [2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)ethyl]dimethylazanium benzenesulfonate monohydrate}, C17H28NO2+·C6H5O3S-·H2O, is a besylate salt hydrate of the antidepressant drug venlafaxine. In the crystal, besylate anions and water molecules self-assemble, forming hydrogen-bonded dimers linked around inversion centers, with graph set R44(6). The crystal packing features a chain of alternate dimers and venlafaxine cations in the b-axis direction with the components linked by O-H...O hydrogen bonds and C-H...O and C-H...[pi] interactions. This is the first example of a venlafaxine cation with a closed conformation, as it features an intramolecular N-H...O interaction involving the protonated N atom.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
International Union of Crystallography
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
Single-Crystal
dc.subject
X-Ray Study
dc.subject.classification
Otras Ciencias Físicas
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Ciencias Físicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Venlafaxine besylate monohydrate
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-09-07T16:55:49Z
dc.journal.volume
69
dc.journal.pagination
1737-1738
dc.journal.pais
Reino Unido
dc.journal.ciudad
Chester
dc.description.fil
Fil: Corvalán Moya, Carolina del Huerto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
dc.description.fil
Fil: Vega, Daniel Roberto. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Constituyentes. Gerencia de Investigación y Aplicaciones; Argentina
dc.journal.title
Acta Crystallographica Section E: Crystallographic Communications
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://scripts.iucr.org/cgi-bin/paper?S1600536813027542
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1107/S1600536813027542
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885021/
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