Mostrar el registro sencillo del ítem
dc.contributor.author
Kahhaleh, Fariz G.
dc.contributor.author
Barrientos, Gabriela Laura
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
Conrad, Melanie L.
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.date.available
2024-05-30T14:47:38Z
dc.date.issued
2024-01
dc.identifier.citation
Kahhaleh, Fariz G.; Barrientos, Gabriela Laura; Conrad, Melanie L.; The gut-lung axis and asthma susceptibility in early life; John Wiley & Sons Ltd; Acta Physiologica; 240; 3; 1-2024; 1-15
dc.identifier.uri
http://hdl.handle.net/11336/236579
dc.description.abstract
Asthma is the most common chronic disease among children, with more than 300million cases worldwide. Over the past several decades, asthma incidence has grown, and epidemiological studies identify the modernized lifestyle as playing a strong contributing role in this phenomenon. In particular, lifestyle factors that modify the maternal gut microbiome during pregnancy, or the infant microbiome in early life, can act as developmental programming events which determine health or disease susceptibility later in life. Microbial colonization of the gut begins at birth, and factors such as delivery mode, breastfeeding, diet, antibiotic use, and exposure to environmental bacteria influence the development of the infant microbiome. Colonization of the gut microbiome is crucial for proper immune system development and disruptions to this process can predispose a child to asthma development. Here, we describe the importance of early-life events for shaping immune responses along the gut-lung axis and why they may provide a window of opportunity for asthma prevention.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
John Wiley & Sons Ltd
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
ANTIBIOTIC
dc.subject
ASTHMA
dc.subject
DOHAD
dc.subject
EARLY LIFE
dc.subject
GUT-LUNG AXIS
dc.subject
HYGIENE HYPOTHESIS
dc.subject
MICROBIOME
dc.subject.classification
Inmunología
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
Medicina Básica
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.title
The gut-lung axis and asthma susceptibility in early life
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-05-16T12:40:47Z
dc.identifier.eissn
1748-1716
dc.journal.volume
240
dc.journal.number
3
dc.journal.pagination
1-15
dc.journal.pais
Reino Unido
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.journal.ciudad
Oxford
dc.description.fil
Fil: Kahhaleh, Fariz G.. Humboldt-Universität zu Berlin; Alemania
dc.description.fil
Fil: Barrientos, Gabriela Laura. Hospital Alemán; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Conrad, Melanie L.. Humboldt-Universität zu Berlin; Alemania
dc.journal.title
Acta Physiologica
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/apha.14092
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/apha.14092
Archivos asociados