Artículo
Single and joint toxicity of azoxystrobin and cyproconazole to Prochilodus lineatus: Bioconcentration and biochemical responses
Fecha de publicación:
01/2024
Editorial:
Elsevier
Revista:
Science of the Total Environment
ISSN:
0048-9697
e-ISSN:
1879-1026
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Fungicides are widely used across the world to protect crops and their presence in freshwater systems is increasing. However, the evaluation of their potential impacts on non-target organisms is in the minority of studies related to pesticides. In the current research, the single and joint toxicity of azoxystrobin (AZX) and cyproconazole (CYP) was investigated in juvenile fish Prochilodus lineatus. In particular, we evaluated bioconcentration and biochemical responses following a short-term exposure to environmentally relevant concentrations of the fungicides (alone and in mixture). We also determined interactions between the biological responses when the two compounds were used in mixture. Our results demonstrate that AZX and CYP pose a risk to native freshwater fish by causing deleterious effects. Both compounds, alone and in mixture, bioaccumulated in P. lineatus and triggered neurotoxicity and changes in oxidative stress biomarkers in several organs. Moreover, muscle was a target tissue for these fungicides and a synergistic interaction was observed for the mixture. Due to the lack of studies in fish assessing the effects following exposure to AZX-CYP mixtures and considering a realistic exposure situation in agriculture-impacted water bodies, these findings provide new and relevant information for future studies.
Palabras clave:
BIOACCUMULATION
,
ECOTOXICOLOGY
,
FISH
,
FUNGICIDES
,
NEUROTOXICITY
,
OXIDATIVE STRESS
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - SANTA FE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Articulos(INALI)
Articulos de INST.NAC.DE LIMNOLOGIA (I)
Articulos de INST.NAC.DE LIMNOLOGIA (I)
Citación
Rossi, Andrea Silvana; Michlig, Melina Paola; Repetti, María Rosa; Cazenave, Jimena; Single and joint toxicity of azoxystrobin and cyproconazole to Prochilodus lineatus: Bioconcentration and biochemical responses; Elsevier; Science of the Total Environment; 907; 1-2024; 1-11
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