Artículo
Bacteria metabolic adaptation to oxidative stress: the case of silica
Perullini, Ana Mercedes
; Dulhoste Vivien, Sophie; Ribot, François; Pehau-Arnaudet, Gérard; Bouvet, Odile; Livage, Jacques; Nassif, Nadine
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Fecha de publicación:
09/2023
Editorial:
Elsevier Science
Revista:
Journal of Biotechnology
ISSN:
0168-1656
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Although the presence of silica in many living organisms offers advanced properties including cell protection, the different in vitro attempts to build living materials in pure silica never favoured the cells viability. Thus, little attention has been paid to host-guest interactions to modify the expected biologic response. Here we report the physiological changes undergone by Escherichia coli K-12 in silica from colloidal solution to gel confinement. We show that the physiological alterations in growing cultures are not triggered by the initial oxidative Reactive Oxygen Species (ROS) response. Silica promotes the induction of alternative metabolic pathways along with an increase of growth suggesting the existence of rpoS polymorphisms. Since the functionality of hybrid materials depends on the specific biologic responses of their guests, such cell physiological adaptation opens perspectives in the design of bioactive devices attracting for a large field of sciences.
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Articulos(INQUIMAE)
Articulos de INST.D/QUIM FIS D/L MATERIALES MEDIOAMB Y ENERGIA
Articulos de INST.D/QUIM FIS D/L MATERIALES MEDIOAMB Y ENERGIA
Citación
Perullini, Ana Mercedes; Dulhoste Vivien, Sophie; Ribot, François; Pehau-Arnaudet, Gérard; Bouvet, Odile; et al.; Bacteria metabolic adaptation to oxidative stress: the case of silica; Elsevier Science; Journal of Biotechnology; 374; 9-2023; 80-89
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