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dc.contributor.author
Talevi, Alan  
dc.contributor.author
Bellera, Carolina Leticia  
dc.contributor.other
Talevi, Alan  
dc.date.available
2023-01-23T15:29:43Z  
dc.date.issued
2021  
dc.identifier.citation
Talevi, Alan; Bellera, Carolina Leticia; Phase 0 and phase III transport; Springer; 2021; 1-8  
dc.identifier.isbn
978-3-030-51519-5  
dc.identifier.uri
http://hdl.handle.net/11336/185284  
dc.description.abstract
The denomination “Phase 0” and “Phase III” transport refers, respectively, to the uptake and efflux transport mechanisms in drug elimination organs. It expands the classic Phase I and Phase II classification of drug-metabolizing reactions, reflecting the highly coordinated functions of biotransformation enzymes and xenobiotic transporters. Phase 0 transport and Phase III transport have sometimes been termed Phase 0 and Phase III metabolism and Phase 0 and Phase III reactions, which might be misleading denominations as the substrate of drug transport systems is not chemically modified during the transport process.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
DRUG EXCRETION  
dc.subject
DRUG ELIMINATION  
dc.subject
DRUG CLEARENCE  
dc.subject
ABC TRANSPORTERS  
dc.subject.classification
Otras Ciencias Biológicas  
dc.subject.classification
Ciencias Biológicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Phase 0 and phase III transport  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/bookPart  
dc.type
info:ar-repo/semantics/parte de libro  
dc.date.updated
2022-12-06T11:21:08Z  
dc.journal.pagination
1-8  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Basignstoke  
dc.description.fil
Fil: Talevi, Alan. Universidad Nacional de La Plata. Facultad de Ciencas Exactas. Laboratorio de Investigación y Desarrollo de Bioactivos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina  
dc.description.fil
Fil: Bellera, Carolina Leticia. Universidad Nacional de La Plata. Facultad de Ciencas Exactas. Laboratorio de Investigación y Desarrollo de Bioactivos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/referenceworkentry/10.1007/978-3-030-51519-5_66-1  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1007/978-3-030-51519-5_66-1  
dc.conicet.paginas
1500  
dc.source.titulo
The ADME encyclopedia: A comprehensive guide on biopharmacy and pharmacokinetics