Capítulo de Libro

Phase 0 and phase III transport

Título del libro: The ADME encyclopedia: A comprehensive guide on biopharmacy and pharmacokinetics

Talevi, AlanIcon ; Bellera, Carolina LeticiaIcon
Otros responsables: Talevi, AlanIcon
Fecha de publicación: 2021
Editorial: Springer
ISBN: 978-3-030-51519-5
Idioma: Inglés
Clasificación temática:

Resumen

The denomination “Phase 0” and “Phase III” transport refers, respectively, to the uptake and efflux transport mechanisms in drug elimination organs. It expands the classic Phase I and Phase II classification of drug-metabolizing reactions, reflecting the highly coordinated functions of biotransformation enzymes and xenobiotic transporters. Phase 0 transport and Phase III transport have sometimes been termed Phase 0 and Phase III metabolism and Phase 0 and Phase III reactions, which might be misleading denominations as the substrate of drug transport systems is not chemically modified during the transport process.
Palabras clave: DRUG EXCRETION , DRUG ELIMINATION , DRUG CLEARENCE , ABC TRANSPORTERS
 
Archivos asociados
Tamaño: 387.9Kb
Formato: PDF
.
Licencia
info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/185284
URL: https://link.springer.com/referenceworkentry/10.1007/978-3-030-51519-5_66-1
DOI: https://doi.org/10.1007/978-3-030-51519-5_66-1
Colecciones
Capítulos de libros(CCT - LA PLATA)
Capítulos de libros de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Talevi, Alan; Bellera, Carolina Leticia; Phase 0 and phase III transport; Springer; 2021; 1-8
Compartir
Altmétricas