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dc.contributor.author
Oliveira Nogueira, Pedro Paulo
dc.contributor.author
de Almeida Gonçalves Amorim, Gabrielle Bueno
dc.contributor.author
Marquez de Oliveira, Odilon
dc.contributor.author
Demyda Peyrás, Sebastián
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dc.contributor.author
Mendonça Santos, Bruna
dc.contributor.author
Souza Lima Silveira da Mota, Lígia
dc.date.available
2022-08-22T13:54:52Z
dc.date.issued
2021-09
dc.identifier.citation
Oliveira Nogueira, Pedro Paulo; de Almeida Gonçalves Amorim, Gabrielle Bueno; Marquez de Oliveira, Odilon; Demyda Peyrás, Sebastián; Mendonça Santos, Bruna; et al.; Sex Reversal Syndrome in an Egyptian Arabian Horse Detected Using Genomic Data – A case report; Elsevier Science Inc.; Journal of Equine Veterinary Science; 104; 103692; 9-2021; 1-6
dc.identifier.issn
0737-0806
dc.identifier.uri
http://hdl.handle.net/11336/166210
dc.description.abstract
A 4-year-old Straight Egyptian Arabian horse was evaluated in 2016 due to a malformation of external genitalia and male sexual behavior. On physical examination, small teats in the inguinal area and a rudi- mentary penis-like structure surrounded by a clitoral fossa could be seen. There was no evidence of vulva and vaginal canal. A stallion like behavior was observed, especially in the presence of mares in heat, when the animal was excited and aggressive and had erection of the penis-like structure. Blood samples were collected for two purposes: hormonal (testosterone and estradiol plasma concentration analyses) and genetic (cytogenetic and molecular analysis). The karyotype showed 32 pairs of chromosomes in all cells (2n = 64) including 14 and 18 pairs of metacentric and acrocentric chromosomes respectively, in agreement with a presumptive 64, XX complement. This result agree with STR and SNP molecular analysis, which also ruled out the possibility of hematopoietic chimerism. In addition, SNP genotyping showed no numerical chromosomal aberrations or large deletions or duplications, that can be linked to the phenotype in any autosome, nor numerical chromosomal abnormalities in the father and mother of the horse analyzed. In conclusion, we determined that the animal in the present study is a male pseudo- hermaphrodite.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science Inc.
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
INTERSEXUAL
dc.subject
PSEUDOHERMAPHRODITE
dc.subject.classification
Tecnología GM, clonación de ganado, selección asistida, diagnósticos, tecnología de producción de biomasa, etc.
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dc.subject.classification
Biotecnología Agropecuaria
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dc.subject.classification
CIENCIAS AGRÍCOLAS
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dc.title
Sex Reversal Syndrome in an Egyptian Arabian Horse Detected Using Genomic Data – A case report
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-08-18T15:56:21Z
dc.journal.volume
104
dc.journal.number
103692
dc.journal.pagination
1-6
dc.journal.pais
Países Bajos
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dc.journal.ciudad
Ámsterdam
dc.description.fil
Fil: Oliveira Nogueira, Pedro Paulo. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
dc.description.fil
Fil: de Almeida Gonçalves Amorim, Gabrielle Bueno. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
dc.description.fil
Fil: Marquez de Oliveira, Odilon. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
dc.description.fil
Fil: Demyda Peyrás, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
dc.description.fil
Fil: Mendonça Santos, Bruna. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
dc.description.fil
Fil: Souza Lima Silveira da Mota, Lígia. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
dc.journal.title
Journal of Equine Veterinary Science
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0737080621003221
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.jevs.2021.103692
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