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dc.contributor.author
Vera, María Inés
dc.contributor.author
Meroño, Tomás
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dc.contributor.author
Urrutia, María Agustina
dc.contributor.author
Parisi, Carina
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Morosan, Yanina
dc.contributor.author
Rosmarin, Melanie
dc.contributor.author
Schnitman, Marta
dc.contributor.author
Brites, Fernando Daniel
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dc.contributor.author
Grisendi, Silvio
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Serrano, María Sol
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Luciani, Wilfredo
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Serrano, Leonardo
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Zuk, Carlos
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de Barrio, Guillermo
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Cejas, Claudia
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Faingold, María Cristina
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Brenta, Gabriela
dc.date.available
2017-04-27T19:54:26Z
dc.date.issued
2014-05
dc.identifier.citation
Vera, María Inés; Meroño, Tomás; Urrutia, María Agustina; Parisi, Carina; Morosan, Yanina; et al.; Differential profile of ultrasound findings associated with malignancy in mixed and solid thyroid nodules in an elderly female population; Hindawi Publishing Corporation; Journal of Thyroid Research; 2014; 5-2014; 1-7
dc.identifier.issn
2042-0072
dc.identifier.uri
http://hdl.handle.net/11336/15806
dc.description.abstract
Objective. Ultrasonographic characteristics are associated with thyroid malignancy. Our aim was to compare the diagnostic value of ultrasound features in the detection of thyroid malignancy in both solid and mixed nodules. Methods. We prospectively studied female patients (≥50 years) referred to ultrasound-guided fine needle aspiration biopsy. Ultrasound features considered suspicious were hypoechogenicity, microcalcifications, irregular margins, high anteroposterior (AP)/axial-ratio, and absent halo. Associations were separately assessed in mixed and solid nodules. Results. In a group of 504 elderly female patients (age = years), the frequency of malignant cytology was 6%. Thirty-one percent of nodules were mixed and 60% were solid. The rate of malignant cytology was similar for mixed and solid nodules (7.4 versus 5.8%, : 0.56). While in mixed nodules none of the ultrasound characteristics were associated with malignant cytology, in solid nodules irregular margins and microcalcifications were significant (all ). The combination of irregular margins and/or microcalcifications significantly increased the association with malignant cytology only in solid nodules (OR: 2.76 (95% CI: 1.25–6.10), : 0.012). Conclusions. Ultrasound features were of poor diagnostic value in mixed nodules, which harbored malignant lesions as often as solid nodules. Our findings challenge the recommended minimal size for ultrasound-guided fine needle aspiration biopsy in mixed nodules.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Hindawi Publishing Corporation
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
Thyroid Nodules
dc.subject
Ultrasonographic
dc.subject.classification
Enfermedades Vasculares Periféricas
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dc.subject.classification
Medicina Clínica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Differential profile of ultrasound findings associated with malignancy in mixed and solid thyroid nodules in an elderly female population
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-04-26T14:13:11Z
dc.journal.volume
2014
dc.journal.pagination
1-7
dc.journal.pais
Egipto
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dc.journal.ciudad
El Cairo
dc.description.fil
Fil: Vera, María Inés. Dr. Cesar Milstein Hospital; Argentina
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Fil: Meroño, Tomás. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
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Fil: Urrutia, María Agustina. Dr. Cesar Milstein Hospital; Argentina
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Fil: Parisi, Carina. Dr. Cesar Milstein Hospital; Argentina
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Fil: Morosan, Yanina. Dr. Cesar Milstein Hospital; Argentina
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Fil: Rosmarin, Melanie. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Schnitman, Marta. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Brites, Fernando Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Grisendi, Silvio. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Serrano, María Sol. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Luciani, Wilfredo. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Serrano, Leonardo. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Zuk, Carlos. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: de Barrio, Guillermo. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Cejas, Claudia. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Faingold, María Cristina. Dr. Cesar Milstein Hospital; Argentina
dc.description.fil
Fil: Brenta, Gabriela. Dr. Cesar Milstein Hospital; Argentina
dc.journal.title
Journal of Thyroid Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/jtr/2014/761653/
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1155/2014/761653
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