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dc.contributor.author
Goldsman, Alejandro
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Vazquez, Haydee
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Quilindro, Alberto
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Sicurello, María
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Cazalas, Mariana
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Altcheh, Jaime Marcelo
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González, Nicolás
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Moros, Claudio
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Grippo, María
dc.date.available
2021-11-29T16:54:14Z
dc.date.issued
2021-03
dc.identifier.citation
Goldsman, Alejandro; Vazquez, Haydee; Quilindro, Alberto; Sicurello, María; Cazalas, Mariana; et al.; Left ventricular longitudinal strain and strain rate measurements in paediatric patients in long-term treatment for Chagas disease; Cambridge University Press; Cardiology In The Young; 3-2021; 1-7
dc.identifier.issn
1047-9511
dc.identifier.uri
http://hdl.handle.net/11336/147621
dc.description.abstract
Introduction: Previous echocardiographic studies failed to show residual alterations of heart function in paediatric patients that have received treatment for Chagas disease. While the echocardiogram is the fundamental front-line tool for evaluating heart function, the appearance of new techniques allows a more detailed analysis. We aimed to evaluate systolic and diastolic function with new techniques in a paediatric population with Chagas disease several years after treatment completion. Material and methods: Echocardiograms were obtained from 84 Chagas disease patients (48 female) and 27 healthy controls. All patients had received treatment concluding on average 10 years prior to the study. The prospective analysis considered cardiac dimensions and cardiac function using two-dimensional, M-mode, Doppler and tissue Doppler imaging with emphasis on measuring longitudinal strain in the left ventricle by speckle tracking. Ejection fraction was measured with three-dimensional echocardiography. Results: Patients had an age of 14.2 ± 5.7 years (6-33) at the time of evaluation. Global and segmental motility of the left ventricle was normal in all patients. Ejection fraction was 59.2 ± 6.5 and 57.4 ± 6.5% (p = 0.31) in patients and controls respectively. Left ventricular global longitudinal systolic strain was -19 ± 2.4% in patients and -19 ± 3.6% (p = 0.91) in controls. No significant differences were found in remaining systolic and diastolic function measurements. Conclusions: Paediatric patients that have received treatment for Chagas disease, evaluated with either conventional techniques or new tools, do not show significant long-term alterations of ventricular function.
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application/pdf
dc.language.iso
eng
dc.publisher
Cambridge University Press
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CARDIAC FUNCTION
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CHAGAS DISEASE
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ECHOCARDIOGRAPHY
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GLOBAL LONGITUDINAL STRAIN
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KEYWORDS:
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PAEDIATRICS
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Enfermedades Infecciosas
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Left ventricular longitudinal strain and strain rate measurements in paediatric patients in long-term treatment for Chagas disease
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-11-18T16:56:49Z
dc.journal.pagination
1-7
dc.journal.pais
Reino Unido
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dc.journal.ciudad
Cambridge
dc.description.fil
Fil: Goldsman, Alejandro. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
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Fil: Vazquez, Haydee. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
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Fil: Quilindro, Alberto. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
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Fil: Sicurello, María. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
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Fil: Cazalas, Mariana. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
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Fil: Altcheh, Jaime Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina. Gobierno de la Ciudad de Buenos Aires. Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas; Argentina
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Fil: González, Nicolás. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
dc.description.fil
Fil: Moros, Claudio. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
dc.description.fil
Fil: Grippo, María. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
dc.journal.title
Cardiology In The Young
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1017/S1047951121000408
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info:eu-repo/semantics/altIdentifier/url/https://www.cambridge.org/core/journals/cardiology-in-the-young/article/abs/left-ventricular-longitudinal-strain-and-strain-rate-measurements-in-paediatric-patients-in-longterm-treatment-for-chagas-disease/5F32513236CE5284B2DCC26489E80A58
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