Artículo
Left ventricular longitudinal strain and strain rate measurements in paediatric patients in long-term treatment for Chagas disease
Goldsman, Alejandro; Vazquez, Haydee; Quilindro, Alberto; Sicurello, María; Cazalas, Mariana; Altcheh, Jaime Marcelo
; González, Nicolás; Moros, Claudio; Grippo, María
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
03/2021
Editorial:
Cambridge University Press
Revista:
Cardiology In The Young
ISSN:
1047-9511
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Introduction: Previous echocardiographic studies failed to show residual alterations of heart function in paediatric patients that have received treatment for Chagas disease. While the echocardiogram is the fundamental front-line tool for evaluating heart function, the appearance of new techniques allows a more detailed analysis. We aimed to evaluate systolic and diastolic function with new techniques in a paediatric population with Chagas disease several years after treatment completion. Material and methods: Echocardiograms were obtained from 84 Chagas disease patients (48 female) and 27 healthy controls. All patients had received treatment concluding on average 10 years prior to the study. The prospective analysis considered cardiac dimensions and cardiac function using two-dimensional, M-mode, Doppler and tissue Doppler imaging with emphasis on measuring longitudinal strain in the left ventricle by speckle tracking. Ejection fraction was measured with three-dimensional echocardiography. Results: Patients had an age of 14.2 ± 5.7 years (6-33) at the time of evaluation. Global and segmental motility of the left ventricle was normal in all patients. Ejection fraction was 59.2 ± 6.5 and 57.4 ± 6.5% (p = 0.31) in patients and controls respectively. Left ventricular global longitudinal systolic strain was -19 ± 2.4% in patients and -19 ± 3.6% (p = 0.91) in controls. No significant differences were found in remaining systolic and diastolic function measurements. Conclusions: Paediatric patients that have received treatment for Chagas disease, evaluated with either conventional techniques or new tools, do not show significant long-term alterations of ventricular function.
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Articulos(IMIPP)
Articulos de INSTITUTO MULTIDISCIPLINARIO DE INVESTIGACIONES EN PATOLOGIAS PEDIATRICAS
Articulos de INSTITUTO MULTIDISCIPLINARIO DE INVESTIGACIONES EN PATOLOGIAS PEDIATRICAS
Citación
Goldsman, Alejandro; Vazquez, Haydee; Quilindro, Alberto; Sicurello, María; Cazalas, Mariana; et al.; Left ventricular longitudinal strain and strain rate measurements in paediatric patients in long-term treatment for Chagas disease; Cambridge University Press; Cardiology In The Young; 3-2021; 1-7
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