Mostrar el registro sencillo del ítem
dc.contributor.author
Postigo, Jose Alberto
dc.contributor.author
Ferreri, Carla
dc.contributor.author
Navacchia, Maria Luisa
dc.contributor.author
Chatgilialoglu, Chryssostomos
dc.date.available
2021-11-29T12:09:06Z
dc.date.issued
2005-12
dc.identifier.citation
Postigo, Jose Alberto; Ferreri, Carla; Navacchia, Maria Luisa; Chatgilialoglu, Chryssostomos; The radical-based reduction with (TMS)3SiH 'on water'; Georg Thieme Verlag Kg; Synlett; 18; 12-2005; 2854-2856
dc.identifier.issn
0936-5214
dc.identifier.uri
http://hdl.handle.net/11336/147592
dc.description.abstract
Reduction of different organohalides, bromonucleosides among them, was successfully carried out in yields ranging from 75% to quantitative, using (TMS)3SiH in a heterogeneous system with water as the solvent. Our procedure, employing 2-mercaptoethanol as the catalyst and the hydrophobic diazo-compound ACCN as the initiator, illustrates that (TMS)3SiH can be the radical-based reducing agent of choice in aqueous medium. (TMS) 3SiH does not suffer from any significant reaction with water and can safely be used with additional benefit, such as ease of purification and environmental compatibility.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Georg Thieme Verlag Kg
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
AZO COMPOUNDS
dc.subject
RADICAL REACTIONS
dc.subject
REDUCTIONS
dc.subject
THIOLS
dc.subject
TRIS(TRIMETHYLSILYL)SILANE
dc.subject.classification
Química Orgánica
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
The radical-based reduction with (TMS)3SiH 'on water'
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-07-26T17:16:41Z
dc.journal.number
18
dc.journal.pagination
2854-2856
dc.journal.pais
Alemania
dc.journal.ciudad
Stuttgart
dc.description.fil
Fil: Postigo, Jose Alberto. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
dc.description.fil
Fil: Ferreri, Carla. Consiglio Nazionale delle Ricerche; Italia
dc.description.fil
Fil: Navacchia, Maria Luisa. Consiglio Nazionale delle Ricerche; Italia
dc.description.fil
Fil: Chatgilialoglu, Chryssostomos. Consiglio Nazionale delle Ricerche; Italia
dc.journal.title
Synlett
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.com/ejournals/abstract/synlett/doi/10.1055/s-2005-918917
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1055/s-2005-918917
Archivos asociados
Tamaño:
81.17Kb
Formato:
PDF