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dc.contributor.author
Veaute, Carolina Melania Isabel  
dc.contributor.author
Liu, D. Y.  
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Furlong, L. I.  
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Biancotti, J. C.  
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Baker, H.  
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Vazquez, Monica Hebe  
dc.date.available
2017-03-27T15:49:53Z  
dc.date.issued
2010-05-01  
dc.identifier.citation
Veaute, Carolina Melania Isabel; Liu, D. Y.; Furlong, L. I.; Biancotti, J. C.; Baker, H. ; et al.; Anti-human proacrosin antibody inhibits the zona pellucida (ZP)-induced acrosome reaction of ZP-bound spermatozoa; Elsevier Inc; Fertility And Sterility; 93; 7; 1-5-2010; 2456-2459  
dc.identifier.issn
0015-0282  
dc.identifier.uri
http://hdl.handle.net/11336/14258  
dc.description.abstract
The anti-acrosin monoclonal antibody AcrC5F10 inhibited proacrosin activation, proacrosin-human zona pellucida glycoprotein A (ZPA) binding, and the zona pellucida (ZP)-induced acrosome reaction of the ZP-bound spermatozoa but had no significant effect on sperm-ZP binding. These results suggest that proacrosin-acrosin may play an important role in the ZP-induced acrosome reaction of spermatozoa after primary binding to the ZP.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Inc  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/  
dc.subject
Human  
dc.subject
Fertilization  
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Spermatozoa  
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Oocyte  
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Proacrosin  
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Acrosin  
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Antibodies  
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Acrosome Reaction  
dc.subject.classification
Inmunología  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Anti-human proacrosin antibody inhibits the zona pellucida (ZP)-induced acrosome reaction of ZP-bound spermatozoa  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-03-23T18:24:15Z  
dc.identifier.eissn
1556-5653  
dc.journal.volume
93  
dc.journal.number
7  
dc.journal.pagination
2456-2459  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva York  
dc.description.fil
Fil: Veaute, Carolina Melania Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina  
dc.description.fil
Fil: Liu, D. Y.. The University Of Melbourne; Australia  
dc.description.fil
Fil: Furlong, L. I.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina  
dc.description.fil
Fil: Biancotti, J. C.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina  
dc.description.fil
Fil: Baker, H. . The University Of Melbourne; Australia  
dc.description.fil
Fil: Vazquez, Monica Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina  
dc.journal.title
Fertility And Sterility  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.fertstert.org/article/S0015-0282(09)03518-3/abstract  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.fertnstert.2009.08.040