Artículo
Anti-human proacrosin antibody inhibits the zona pellucida (ZP)-induced acrosome reaction of ZP-bound spermatozoa
Veaute, Carolina Melania Isabel; Liu, D. Y.; Furlong, L. I.; Biancotti, J. C.; Baker, H. ; Vazquez, Monica Hebe
Fecha de publicación:
01/05/2010
Editorial:
Elsevier Inc
Revista:
Fertility And Sterility
ISSN:
0015-0282
e-ISSN:
1556-5653
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The anti-acrosin monoclonal antibody AcrC5F10 inhibited proacrosin activation, proacrosin-human zona pellucida glycoprotein A (ZPA) binding, and the zona pellucida (ZP)-induced acrosome reaction of the ZP-bound spermatozoa but had no significant effect on sperm-ZP binding. These results suggest that proacrosin-acrosin may play an important role in the ZP-induced acrosome reaction of spermatozoa after primary binding to the ZP.
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Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Veaute, Carolina Melania Isabel; Liu, D. Y.; Furlong, L. I.; Biancotti, J. C.; Baker, H. ; et al.; Anti-human proacrosin antibody inhibits the zona pellucida (ZP)-induced acrosome reaction of ZP-bound spermatozoa; Elsevier Inc; Fertility And Sterility; 93; 7; 1-5-2010; 2456-2459
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