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dc.contributor.author
Moyano, María A.  
dc.contributor.author
Broussalis, Adriana M.  
dc.contributor.author
Segall, Adriana Ines  
dc.date.available
2017-03-21T20:48:17Z  
dc.date.issued
2010-02  
dc.identifier.citation
Moyano, María A.; Broussalis, Adriana M.; Segall, Adriana Ines; Thermal analysis of lipoic acid and evaluation of the compatibility with excipients; Springer; Journal of Thermal Analysis and Calorimetry; 99; 2; 2-2010; 631-637  
dc.identifier.issn
1388-6150  
dc.identifier.uri
http://hdl.handle.net/11336/14152  
dc.description.abstract
Differential scanning calorimetry (DSC) was used as a screening technique for assessing the compatibility of lipoic acid with some currently employed cosmetic excipients. In the first phase of the study DSC was used as a tool to detect any interaction. Based on the DSC results alone, methyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butylated hydroxytoluene, non ionic self emulsifying wax, propylene glycol and acetylated lanolin were found to exhibit interaction with lipoic acid. Stressed binary mixtures (stored at 50 °C for 1 week) of lipoic acid and excipients were evaluated by HPLC. Binary mixtures were evaluated by IR spectroscopy.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Compatibility Study  
dc.subject
Differential Scanning Calorimetry  
dc.subject
Lipoic Acid  
dc.subject
Hplc  
dc.subject
Ir  
dc.subject.classification
Química Analítica  
dc.subject.classification
Ciencias Químicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Thermal analysis of lipoic acid and evaluation of the compatibility with excipients  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-03-21T20:13:33Z  
dc.identifier.eissn
1572-8943  
dc.journal.volume
99  
dc.journal.number
2  
dc.journal.pagination
631-637  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Dordrecht  
dc.description.fil
Fil: Moyano, María A.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina  
dc.description.fil
Fil: Broussalis, Adriana M.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Farmacognosia; Argentina  
dc.description.fil
Fil: Segall, Adriana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina  
dc.journal.title
Journal of Thermal Analysis and Calorimetry  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10973-009-0351-6  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s10973-009-0351-6  

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