Artículo

Thermal analysis of lipoic acid and evaluation of the compatibility with excipients

Moyano, María A.; Broussalis, Adriana Maria; Segall, Adriana InesIcon
Fecha de publicación: 02/2010
Editorial: Springer
Revista: Journal of Thermal Analysis and Calorimetry
ISSN: 1388-6150
e-ISSN: 1572-8943
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Differential scanning calorimetry (DSC) was used as a screening technique for assessing the compatibility of lipoic acid with some currently employed cosmetic excipients. In the first phase of the study DSC was used as a tool to detect any interaction. Based on the DSC results alone, methyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butylated hydroxytoluene, non ionic self emulsifying wax, propylene glycol and acetylated lanolin were found to exhibit interaction with lipoic acid. Stressed binary mixtures (stored at 50 °C for 1 week) of lipoic acid and excipients were evaluated by HPLC. Binary mixtures were evaluated by IR spectroscopy.
Palabras clave: Compatibility Study , Differential Scanning Calorimetry , Lipoic Acid , Hplc , Ir
 
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/14152
URL: https://link.springer.com/article/10.1007%2Fs10973-009-0351-6
DOI: http://dx.doi.org/10.1007/s10973-009-0351-6
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Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Moyano, María A.; Broussalis, Adriana Maria; Segall, Adriana Ines; Thermal analysis of lipoic acid and evaluation of the compatibility with excipients; Springer; Journal of Thermal Analysis and Calorimetry; 99; 2; 2-2010; 631-637
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