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dc.contributor.author
Facchinetti, Fabio  
dc.contributor.author
Espinola, Maria Salome Bezerra  
dc.contributor.author
Dewailly, Didier  
dc.contributor.author
Ozay, Ali Cenk  
dc.contributor.author
Prapas, Nikos  
dc.contributor.author
Vazquez, Monica Hebe  
dc.contributor.author
Wdowiak, Artur  
dc.contributor.author
Unfer, Vittorio  
dc.contributor.author
Expert Group on Inositols in Preclinical and Clinical Research  
dc.contributor.author
Appetecchia, Marialuisa  
dc.contributor.author
Aragona, Cesare  
dc.contributor.author
Bertelli, Matteo  
dc.contributor.author
Bevilacqua, Arturo  
dc.contributor.author
Bizzarri, Mariano  
dc.contributor.author
Cavalli, Pietro  
dc.contributor.author
Copp, Andrew  
dc.contributor.author
D'Anna, Rosario  
dc.contributor.author
Greene, Nicholas  
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Marín, Imelda Hernández  
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Kamenov, Zdravko A.  
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Kandaraki, Eleni  
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Diamanti Kandarakis, Evanthia  
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Laganà, Antonio Simone  
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Monastra, Giovanni  
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Oliva, Mario Montanino  
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Nestler, John E.  
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Papalou, Olga  
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Pkhaladze, Lali  
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Porcaro, Giusy  
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Soulage, Christophe O.  
dc.contributor.author
Stringaro, Annarita  
dc.date.available
2021-09-19T16:30:15Z  
dc.date.issued
2020-08  
dc.identifier.citation
Facchinetti, Fabio; Espinola, Maria Salome Bezerra; Dewailly, Didier; Ozay, Ali Cenk; Prapas, Nikos; et al.; Breakthroughs in the use of inositol for Assisted Reproductive Treatment (ART); Elsevier Science London; Trends In Endocrinology And Metabolism; 31; 8; 8-2020; 570-579  
dc.identifier.issn
1043-2760  
dc.identifier.uri
http://hdl.handle.net/11336/140792  
dc.description.abstract
It is well known that myo-inositol (MI) and D-chiro-inositol (DCI) are insulinsensitizingagents, and MI is of proven utility in polycystic ovary syndrome(PCOS). In addition, MI plays a pivotal role in the physiology of reproduction,and has beneficial effects on the development of oocytes, spermatozoa, andembryos. By contrast, DCI has little effect on spermatozoa, but high concentrationsin the ovary can negatively affect the quality of oocytes and the blastocyst.Overall, the evidence in the literature supports the beneficial effects of MI in bothfemale and male reproduction, warranting clinical use of MI in assistedreproductive treatment (ART).  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Science London  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
HUMAN FERTILITY  
dc.subject
INOSITOL  
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ASSISTED REPRODUCTIVE TECHNOLOGY  
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INFERTILITY  
dc.subject.classification
Bioquímica y Biología Molecular  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Breakthroughs in the use of inositol for Assisted Reproductive Treatment (ART)  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-08-05T16:54:38Z  
dc.identifier.eissn
1879-3061  
dc.journal.volume
31  
dc.journal.number
8  
dc.journal.pagination
570-579  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
London  
dc.description.fil
Fil: Facchinetti, Fabio. Università Di Modena E Reggio Emilia.; Italia  
dc.description.fil
Fil: Espinola, Maria Salome Bezerra. Università degli studi di Roma "La Sapienza"; Italia  
dc.description.fil
Fil: Dewailly, Didier. Inserm; Francia. University Of Lille.; Francia  
dc.description.fil
Fil: Ozay, Ali Cenk. Near East University; Chipre  
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Fil: Prapas, Nikos. Aristotle University Of Thessaloniki; Grecia. Iakentro Fertility Centre; Grecia  
dc.description.fil
Fil: Vazquez, Monica Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina  
dc.description.fil
Fil: Wdowiak, Artur. Medical University Of Lublin; Polonia  
dc.description.fil
Fil: Unfer, Vittorio. Università degli studi di Roma "La Sapienza"; Italia  
dc.description.fil
Fil: Expert Group on Inositols in Preclinical and Clinical Research. No especifíca;  
dc.description.fil
Fil: Appetecchia, Marialuisa. Istituto Nazionale Tumori Regina Elena; Italia  
dc.description.fil
Fil: Aragona, Cesare. Università degli studi di Roma "La Sapienza"; Italia  
dc.description.fil
Fil: Bertelli, Matteo. EBTNA Laboratory; Italia. MAGI Laboratory; Italia  
dc.description.fil
Fil: Bevilacqua, Arturo. Università degli studi di Roma "La Sapienza"; Italia  
dc.description.fil
Fil: Bizzarri, Mariano. Università degli studi di Roma "La Sapienza"; Italia  
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Fil: Cavalli, Pietro. ASST Cremona. Clinical Genetics; Italia  
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Fil: Copp, Andrew. Colegio Universitario de Londres; Reino Unido  
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Fil: D'Anna, Rosario. Università Degli Studi Di Messina; Italia  
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Fil: Greene, Nicholas. Colegio Universitario de Londres; Reino Unido  
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Fil: Marín, Imelda Hernández. Universidad Nacional Autónoma de México; México. Hospital Juarez; México  
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Fil: Kamenov, Zdravko A.. Medical University of Sofia; Bulgaria  
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Fil: Kandaraki, Eleni. HYGEIA Hospital; Grecia  
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Fil: Diamanti Kandarakis, Evanthia. HYGEIA Hospital; Grecia  
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Fil: Laganà, Antonio Simone. University of Insubria; Italia  
dc.description.fil
Fil: Monastra, Giovanni. Università degli studi di Roma "La Sapienza"; Italia  
dc.description.fil
Fil: Oliva, Mario Montanino. Ospedale Generale Santo Spirito; Italia  
dc.description.fil
Fil: Nestler, John E.. Virginia Commonwealth University; Estados Unidos  
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Fil: Papalou, Olga. HYGEIA Hospital; Grecia  
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Fil: Pkhaladze, Lali. Ioseb Zhordania Institute of Reproductology; Georgia  
dc.description.fil
Fil: Porcaro, Giusy. Azienda Unità Sanitaria Locale Umbria 2.; Italia  
dc.description.fil
Fil: Soulage, Christophe O.. Université Claude Bernard Lyon 1; Francia. Inserm; Francia  
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Fil: Stringaro, Annarita. Istituto Superiore di Sanità ; Italia  
dc.journal.title
Trends In Endocrinology And Metabolism  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S1043276020300801  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.tem.2020.04.003