Artículo

Breakthroughs in the use of inositol for Assisted Reproductive Treatment (ART)

Facchinetti, Fabio; Espinola, Maria Salome Bezerra; Dewailly, Didier; Ozay, Ali Cenk; Prapas, Nikos; Vazquez, Monica HebeIcon ; Wdowiak, Artur; Unfer, Vittorio; Expert Group on Inositols in Preclinical and Clinical Research; Appetecchia, Marialuisa; Aragona, Cesare; Bertelli, Matteo; Bevilacqua, Arturo; Bizzarri, Mariano; Cavalli, Pietro; Copp, Andrew; D'Anna, Rosario; Greene, Nicholas; Marín, Imelda Hernández; Kamenov, Zdravko A.; Kandaraki, Eleni; Diamanti Kandarakis, Evanthia; Laganà, Antonio Simone; Monastra, Giovanni; Oliva, Mario Montanino; Nestler, John E.; Papalou, Olga; Pkhaladze, Lali; Porcaro, Giusy; Soulage, Christophe O.; Stringaro, Annarita
Fecha de publicación: 08/2020
Editorial: Elsevier Science London
Revista: Trends In Endocrinology And Metabolism
ISSN: 1043-2760
e-ISSN: 1879-3061
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

It is well known that myo-inositol (MI) and D-chiro-inositol (DCI) are insulinsensitizingagents, and MI is of proven utility in polycystic ovary syndrome(PCOS). In addition, MI plays a pivotal role in the physiology of reproduction,and has beneficial effects on the development of oocytes, spermatozoa, andembryos. By contrast, DCI has little effect on spermatozoa, but high concentrationsin the ovary can negatively affect the quality of oocytes and the blastocyst.Overall, the evidence in the literature supports the beneficial effects of MI in bothfemale and male reproduction, warranting clinical use of MI in assistedreproductive treatment (ART).
Palabras clave: HUMAN FERTILITY , INOSITOL , ASSISTED REPRODUCTIVE TECHNOLOGY , INFERTILITY
 
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/140792
URL: https://linkinghub.elsevier.com/retrieve/pii/S1043276020300801
DOI: http://dx.doi.org/10.1016/j.tem.2020.04.003
Colecciones
Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Facchinetti, Fabio; Espinola, Maria Salome Bezerra; Dewailly, Didier; Ozay, Ali Cenk; Prapas, Nikos; et al.; Breakthroughs in the use of inositol for Assisted Reproductive Treatment (ART); Elsevier Science London; Trends In Endocrinology And Metabolism; 31; 8; 8-2020; 570-579
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