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dc.contributor.author
Silva, Berenice Anabel  
dc.contributor.author
Miglietta, Esteban Alberto  
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Ferrari, Carina Cintia  
dc.date.available
2021-08-30T12:32:50Z  
dc.date.issued
2020-07  
dc.identifier.citation
Silva, Berenice Anabel; Miglietta, Esteban Alberto; Ferrari, Carina Cintia; Training the brain: Could it improve multiple sclerosis treatment?; Freund & Pettman Publishers; Reviews In The Neurosciences; 31; 7; 7-2020; 779-792  
dc.identifier.issn
0334-1763  
dc.identifier.uri
http://hdl.handle.net/11336/139176  
dc.description.abstract
Multiple sclerosis (MS) is a neurological disease characterized by neuroinflammation, demyelination and axonal degeneration along with loss of function in the central nervous system. For many years, research in MShas focused on the efficacy of pharmacological treatments. However, during the last years, many publications have been dedicated to the study of the efficacy of nonpharmacological strategies, such as physical exercise and cognitive training. Beneficial effects of the combination of both strategies on cognitive function have been described in both ageing adults and patients with neurodegenerative diseases, such as MS. The analysis of combining both physical and cognitive stimulation can be summarized by the environmental enrichment (EE) experiments, which are more suitable for animal models. EE refers to housing conditions consisting of exercise and cognitive and social stimulation. In this review, we will summarize the available studies that describe the influence of EE in both MS patients and MS animal models.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Freund & Pettman Publishers  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
ANIMAL MODELS  
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COGNITIVE IMPAIRMENT  
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DEMYELINATION  
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ENVIRONMENTAL ENRICHMENT  
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EXERCISE  
dc.subject.classification
Neurociencias  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Training the brain: Could it improve multiple sclerosis treatment?  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2021-08-20T19:43:23Z  
dc.identifier.eissn
2191-0200  
dc.journal.volume
31  
dc.journal.number
7  
dc.journal.pagination
779-792  
dc.journal.pais
Países Bajos  
dc.description.fil
Fil: Silva, Berenice Anabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional e Ingeniería Biomédica - Hospital Italiano. Instituto de Medicina Traslacional e Ingeniería Biomédica.- Instituto Universitario Hospital Italiano de Buenos Aires. Instituto de Medicina Traslacional e Ingeniería Biomédica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina  
dc.description.fil
Fil: Miglietta, Esteban Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina  
dc.description.fil
Fil: Ferrari, Carina Cintia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Hospital Italiano. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Instituto Universitario Hospital Italiano de Buenos Aires. Instituto de Medicina Traslacional E Ingenieria Biomedica.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina  
dc.journal.title
Reviews In The Neurosciences  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.degruyter.com/document/doi/10.1515/revneuro-2020-0014/html  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1515/revneuro-2020-0014