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Artículo

Training the brain: Could it improve multiple sclerosis treatment?

Silva, Berenice Anabel; Miglietta, Esteban AlbertoIcon ; Ferrari, Carina CintiaIcon
Fecha de publicación: 07/2020
Editorial: Freund & Pettman Publishers
Revista: Reviews In The Neurosciences
ISSN: 0334-1763
e-ISSN: 2191-0200
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:
Neurociencias

Resumen

Multiple sclerosis (MS) is a neurological disease characterized by neuroinflammation, demyelination and axonal degeneration along with loss of function in the central nervous system. For many years, research in MShas focused on the efficacy of pharmacological treatments. However, during the last years, many publications have been dedicated to the study of the efficacy of nonpharmacological strategies, such as physical exercise and cognitive training. Beneficial effects of the combination of both strategies on cognitive function have been described in both ageing adults and patients with neurodegenerative diseases, such as MS. The analysis of combining both physical and cognitive stimulation can be summarized by the environmental enrichment (EE) experiments, which are more suitable for animal models. EE refers to housing conditions consisting of exercise and cognitive and social stimulation. In this review, we will summarize the available studies that describe the influence of EE in both MS patients and MS animal models.
Palabras clave: ANIMAL MODELS , COGNITIVE IMPAIRMENT , DEMYELINATION , ENVIRONMENTAL ENRICHMENT , EXERCISE
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/139176
URL: https://www.degruyter.com/document/doi/10.1515/revneuro-2020-0014/html
DOI: http://dx.doi.org/10.1515/revneuro-2020-0014
Colecciones
Articulos(IIBBA)
Articulos de INST.DE INVEST.BIOQUIMICAS DE BS.AS(I)
Articulos (IMTIB)
Articulos de INSTITUTO DE MEDICINA TRASLACIONAL E INGENIERIA BIOMEDICA
Citación
Silva, Berenice Anabel; Miglietta, Esteban Alberto; Ferrari, Carina Cintia; Training the brain: Could it improve multiple sclerosis treatment?; Freund & Pettman Publishers; Reviews In The Neurosciences; 31; 7; 7-2020; 779-792
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