Artículo
Improvements in the acylation of 3-methylindole using amberlyst-15
Fecha de publicación:
02/2020
Editorial:
Bentham Science Publishers
Revista:
Letters in Organic Chemistry
ISSN:
1570-1786
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A simple and efficient methodology for Friedel-Crafts acylation of 3-methylindole using Amberlyst 15 resin as catalyst is described. This methodology shows good selectivity towards the for-mation of the products of 2-acylation, (3-methyl-1H-indol-2-yl)ketones. Several advantages can be as-cribed to Amberlyst 15, among them; are the ease of handling, quick separation from the reaction mix-ture and minimum or no production of the chemical residues that must be eliminated. Besides, the catalyst can be easily recycled and reused with a minimal loss in activity through 6 reaction cycles. The catalyst was characterized by FT-IR spectroscopy and superficial acidity.
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos(CINDECA)
Articulos de CENTRO DE INV EN CS.APLICADAS "DR.JORGE J.RONCO"
Articulos de CENTRO DE INV EN CS.APLICADAS "DR.JORGE J.RONCO"
Citación
Vargas, Dario Andres; Mendez, Leticia Jesica; Cánepa, Alicia Susana; Improvements in the acylation of 3-methylindole using amberlyst-15; Bentham Science Publishers; Letters in Organic Chemistry; 17; 11; 2-2020; 890-896
Compartir
Altmétricas