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dc.contributor.author
Blois, Sandra M.  
dc.contributor.author
Dveksler, Gabriela  
dc.contributor.author
Vasta, Gerardo R.  
dc.contributor.author
Freitag, Nancy  
dc.contributor.author
Blanchard, Véronique  
dc.contributor.author
Barrientos, Gabriela Laura  
dc.date.available
2021-03-19T11:52:10Z  
dc.date.issued
2019-05  
dc.identifier.citation
Blois, Sandra M.; Dveksler, Gabriela; Vasta, Gerardo R.; Freitag, Nancy; Blanchard, Véronique; et al.; Pregnancy galectinology: Insights into a complex network of glycan binding proteins; Frontiers Media S.A.; Frontiers in Immunology; 10; MAY; 5-2019; 1-15  
dc.identifier.issn
1664-3224  
dc.identifier.uri
http://hdl.handle.net/11336/128615  
dc.description.abstract
Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function. Galectins contribute to placentation by regulating trophoblast development, migration, and invasion during early pregnancy. In addition, galectins are critical players regulating maternal immune tolerance to the embedded embryo. Recently, the role of galectins in angiogenesis during decidualization and in placenta formation has gained attention. Altered expression of galectins is associated with abnormal pregnancies and infertility. This review focuses on the role of galectins in pregnancy-associated processes and discusses the relevance of galectin-glycan interactions as potential therapeutic targets in pregnancy disorders.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Frontiers Media S.A.  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/  
dc.subject
GALECTINS  
dc.subject
GLYCANS  
dc.subject
PLACENTATION  
dc.subject
PREECLAMPSIA  
dc.subject
PREGNANCY  
dc.subject.classification
Inmunología  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Pregnancy galectinology: Insights into a complex network of glycan binding proteins  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2021-03-05T18:34:26Z  
dc.journal.volume
10  
dc.journal.number
MAY  
dc.journal.pagination
1-15  
dc.journal.pais
Suiza  
dc.description.fil
Fil: Blois, Sandra M.. Universität zu Berlin; Alemania  
dc.description.fil
Fil: Dveksler, Gabriela. No especifíca;  
dc.description.fil
Fil: Vasta, Gerardo R.. University of Maryland; Estados Unidos  
dc.description.fil
Fil: Freitag, Nancy. Universität zu Berlin; Alemania  
dc.description.fil
Fil: Blanchard, Véronique. Universität zu Berlin; Alemania  
dc.description.fil
Fil: Barrientos, Gabriela Laura. Universidad de Buenos Aires; Argentina. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.journal.title
Frontiers in Immunology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fimmu.2019.01166  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fimmu.2019.01166/full  

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