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dc.contributor.author
Moreira Pazin, Wallance  
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Santos, Suikinai N. Dos  
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Queiroz, Sonia C. N.  
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Bagatolli, Luis Alberto  
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Soares, Ademilson E. E.  
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Melo, Itamar S. de  
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Ito, Amando S.  
dc.date.available
2021-03-18T20:05:25Z  
dc.date.issued
2019-07  
dc.identifier.citation
Moreira Pazin, Wallance; Santos, Suikinai N. Dos; Queiroz, Sonia C. N.; Bagatolli, Luis Alberto; Soares, Ademilson E. E.; et al.; Bioactivity and action mechanism of green propolis against Pythium aphanidermatum; Academia Brasileira de Ciencias; Anais da Academia Brasileira de Ciencias; 91; 2; 7-2019; 1-9  
dc.identifier.uri
http://hdl.handle.net/11336/128584  
dc.description.abstract
We have established how natural compounds from green propolis collected by the species Apis mellifera act against the growth of Pythium aphanidermatum. On the basis of mass spectrometry (Q-ToF MS), we determined that Artepillin C, the major constituent of green propolis, underlies the effect and displays activity against P. aphanidermatum at a minimal inhibitory concentration of 750 µg.mL-1. Biophysical studies based on model membranes showed that this inhibitory effect may be linked with a membrane-related phenomenon: Artepillin C increases the permeability of membranes with relatively high fluidity in their lateral structure, a feature that is in line with the lipid composition reported for the cytoplasmic membrane of P. aphanidermatum. Therefore, the present study supports the use of the effective and inexpensive green propolis to control the impact of the dangerous phytopathogen P. aphanidermatum on agriculture.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Academia Brasileira de Ciencias  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
ARTEPILLIN C  
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FUNGICIDE  
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GREEN PROPOLIS  
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MODEL MEMBRANES  
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PYTHIUM APHANIDERMATUM  
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Biofísica  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Bioactivity and action mechanism of green propolis against Pythium aphanidermatum  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-11-19T21:19:14Z  
dc.identifier.eissn
1678-2690  
dc.journal.volume
91  
dc.journal.number
2  
dc.journal.pagination
1-9  
dc.journal.pais
Brasil  
dc.journal.ciudad
Río de Janeiro  
dc.description.fil
Fil: Moreira Pazin, Wallance. Universidade de Sao Paulo; Brasil  
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Fil: Santos, Suikinai N. Dos. Laboratório de Microbiologia Ambiental; Brasil  
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Fil: Queiroz, Sonia C. N.. Laboratório de Microbiologia Ambiental; Brasil  
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Fil: Bagatolli, Luis Alberto. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina  
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Fil: Soares, Ademilson E. E.. Universidade de Sao Paulo; Brasil  
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Fil: Melo, Itamar S. de. Laboratório de Microbiologia Ambiental; Brasil  
dc.description.fil
Fil: Ito, Amando S.. Universidade de Sao Paulo; Brasil  
dc.journal.title
Anais da Academia Brasileira de Ciencias  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1590/0001-3765201920180598  
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info:eu-repo/semantics/altIdentifier/url/http://ref.scielo.org/w5m3sk