Artículo
Bioactivity and action mechanism of green propolis against Pythium aphanidermatum
Moreira Pazin, Wallance; Santos, Suikinai N. Dos; Queiroz, Sonia C. N.; Bagatolli, Luis Alberto
; Soares, Ademilson E. E.; Melo, Itamar S. de; Ito, Amando S.
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
07/2019
Editorial:
Academia Brasileira de Ciencias
Revista:
Anais da Academia Brasileira de Ciencias
e-ISSN:
1678-2690
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
We have established how natural compounds from green propolis collected by the species Apis mellifera act against the growth of Pythium aphanidermatum. On the basis of mass spectrometry (Q-ToF MS), we determined that Artepillin C, the major constituent of green propolis, underlies the effect and displays activity against P. aphanidermatum at a minimal inhibitory concentration of 750 µg.mL-1. Biophysical studies based on model membranes showed that this inhibitory effect may be linked with a membrane-related phenomenon: Artepillin C increases the permeability of membranes with relatively high fluidity in their lateral structure, a feature that is in line with the lipid composition reported for the cytoplasmic membrane of P. aphanidermatum. Therefore, the present study supports the use of the effective and inexpensive green propolis to control the impact of the dangerous phytopathogen P. aphanidermatum on agriculture.
Palabras clave:
ARTEPILLIN C
,
FUNGICIDE
,
GREEN PROPOLIS
,
MODEL MEMBRANES
,
PYTHIUM APHANIDERMATUM
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(INIMEC - CONICET)
Articulos de INSTITUTO DE INV. MEDICAS MERCEDES Y MARTIN FERREYRA
Articulos de INSTITUTO DE INV. MEDICAS MERCEDES Y MARTIN FERREYRA
Citación
Moreira Pazin, Wallance; Santos, Suikinai N. Dos; Queiroz, Sonia C. N.; Bagatolli, Luis Alberto; Soares, Ademilson E. E.; et al.; Bioactivity and action mechanism of green propolis against Pythium aphanidermatum; Academia Brasileira de Ciencias; Anais da Academia Brasileira de Ciencias; 91; 2; 7-2019; 1-9
Compartir
Altmétricas